Correlation Between Transabdominal Chorionic Villus Sampling and Fetal Distress With Color Doppler Sonography
Abstract
Chorionic villus sampling (CVS) is an invasive method for identifying genetic and metabolic diseases, which is done in the first trimester of pregnancy and can cause many complications. The aim of this study is the evaluation of the correlation between Transabdominal chorionic villus sampling and fetal distress in color Doppler sonography. This study is experimental (before and after). All pregnant women with minor thalassemia in which their husbands were suffering from minor thalassemia or have a history of a child with major thalassemia and after the 12th week of pregnancy were referred to the ultrasound department. RI for fetal Middle Cerebral Artery (MCA) and Umbilical Artery (UA) before and after of CVS were measured and then statistically analyzed using SPSS 22. CVS did not cause a significant increase in RI for the fetal middle cerebral artery (P>0.05). CVS did cause a significant increase in RI for the umbilical artery (P<0.05). Then, CVS did cause a significant decrease in the ratio of RI for fetal Middle Cerebral Artery to RI for Umbilical Artery (P<0.05). Based on these results, it seems that CVS can cause distress in the fetus.
2. Carol M.Rumack, Stephanie R. Wilson Y . Williom Charboneau, Deboroh Levine. Diagnostic ultrasound, 4nd ed.Elsevier Mosby , 2011;1546-47.
3. Cunningham , Leveno , Bloom , Hauth , Rouse, spong. Williams obstetrics, 23 rd ed. Mc Graw Hill 2010:429-431.
4. Arthorc.Fleischer, Frank A. Manning, Philippe Jeomty, Roberto Romero. Sonography in Obstetrics & Gynecology: (Principles and Practice) Mc Graw Hill 2001;1:250-251.
5.Paul. L Allan, Paul A.Dubbins, Mayran A.pozniak, W.Normanmcdicken:Clinical Doppler Ultrasound. Churchill Livingstone, Harcourt publisher, 2007:259-263.
6. Martinez JM, Comas C, Ojuel J, Borrell A, Puerto B, Fortuny A. Immediate changes in umbilical blood flow after transcervical chorionic villus sampling performed by biopsy forceps. Prenat Diagn. 1996; 16(3):223-9.
7. Sterne G, Shields LE, Dubinsky TJ. Abnormal fetal cerebral and umbilical Doppler measurements in fetuses with intrauterine growth restriction predicts the severity of perinatal morbidity. J Clin Ultrasound 2001;29(3):146-51.
8.Zoppini C, Ludomirsky A, Godmilow L, Weiner S, Maislin G, Donnenfeld AE.
Acute hemodynamic effects induced by chorionic villus sampling: a preliminary investigation. Am J Obstet Gynecol 1993;169(4):902-7.
9. Ibba R M, Monni G, Olla G, Cao A. Umbilical artery velocity waveforms before and after chorionic villus sampling . Prenat Diagn 1994;14,(9) : 799-802.
10. Hibbard JU, Loy GL, Hibbard MC.Does chorionic villus sampling compromise fetal umbilical blood flow? Prenat Diagn. 1994;14(12):1107-12.
11.Kofinas AD, D'Amico K, McGuiness T, Clay D, King K. Transabdominal chorionic villus sampling at 9.5-12 weeks' gestation. Placental vascular resistance and fetal cardiovascular responses. J Reprod Med. 1995 Jun;40(6):453-7.
12.Khalil A, Akolekar R, Syngelaki A, Penco JM, Nicolaides KH. Effect of chorionic villus sampling on uterine artery Doppler. Fetal Diagn Ther. 2010;28(1):9-13. doi: 10.1159/000315295. Epub 2010 Jul 21.
13. Brezinka C, Hagenaars AM, Wladimiroff JW, Los FJ. Fetal ductus venosus flow velocity waveforms and maternal serum AFP before and after first-trimester transabdominal chorionic villus sampling. Prenat Diagn
14. Yalti S, Oral O, Gürbüz B, Ozden S, Atar F. Ratio of middle cerebral to umbilical artery blood velocity in preeclamptic & hypertensive women in the prediction of poor perinatal outcome. Indian J Med Res 2004;120(1):44-50.
15. Jensen A, Roman C, Rudolph AM. Effects of reducing uterine blood flow on fetal blood flow distribution and oxygen delivery. J Dev Physiol 1991;15(6):309-23.
16. Dubiel M, Gudmundsson S, Gunnarsson G, Marsál K. Middle cerebral artery velocimetry as a predictor of hypoxemia in fetuses with increased resistance to blood flow in the umbilical artery. Early Hum Dev 1997;47(2):177-84.
17. Pattinson R, Dawes G, Jennings J, Redman C. Umbilical artery resistance index as a screening test for fetal well-being. I: Prospective revealed evaluation. Obstet Gynecol 1991; 78(3 Pt 1):353-8.
18. Harneet N, Kapila AK , Kaur M M. Cerebral and umbilical arterial blood flow velocity in normal and growth retarded pregnancy. J Obstet Gynecol India 2009; 59( 1) : 47-52.
19. Neilson JP, Alfirevic Z. Doppler ultrasound for fetal assessment in high risk pregnancies. Cochrane Database Syst Rev 2000;(2):CD000073.
20. Arias F.Accuracy of the middle-cerebral-to-umbilical-artery resistance index ratio in the prediction of neonatal outcome in patients at high risk for fetal and neonatal complications. Am J Obstet Gynecol 1994 ; 171(6):1541-5.
21. Fouda UM, ElKassem M A M, Hefny S M, Hashem A T Role of middle cerebral artery, umbilical artery resistance indices and middle cerebral artery to umbilical artery resistance index ratio in predicting unfavorable perinatal outcomes of normotensive and hypertensive diabetic pregnancies. Life Science Journal 2013; 10( 3): 2371-2377.
Files | ||
Issue | Vol 57, No 12 (2019) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/acta.v57i12.3469 | |
Keywords | ||
Chorionic villus sampling Doppler sonography Fetal distress |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |