Oral Paraneoplastic Pemphigus and Pharyngeal Squamous Cell Carcinoma: A Rare Case Report and Review of Literature
,
Abstract
Paraneoplastic pemphigus (PNP) is an autoimmune vesiculo-bullous disease of skin and mucous membrane associated with benign and malignant neoplasm. Most common malignancies associated with PNP are hematologic and lymphomatoid. Association of oral PNP with squamous cell carcinoma of the pharynx is very scarce, very few cases are reported, and also the cases of PNP are usually refractory to the treatment mainly those associated with hematologic. Here we reported a case of oral paraneoplastic pemphigus with squamous cell carcinoma of the pharynx that resolved on its own after completion of treatment of pharyngeal squamous cell carcinoma.
1. Marta Wieczorek, Annette Czernik. Paraneoplastic pemphigus: a short review. Clin Cosmet Investig Dermatol. 2016; 9: 291–295. 10.2147/CCID.S100802
2. Anhalt GJ, Kim SC, Stanley JR et al. Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med. 1990;323:1729–1735. 10.1056/NEJM199012203232503
3. Lee SE, Kim SC. Paraneoplastic pemphigus. Dermatol Sin 2010;28:1–14. 10.23937/2469-5750/1510046
4. Kaplan I, Hodak E, Ackerman L, et al. Neoplasms associated with paraneoplastic pemphigus: A review with emphasis on nonhematologic malignancy and oral mucosal manifestations. Oral Oncol 2004;40:553–62. 10.1016/j.oraloncology.2003.09.020
5. Wong KC, Ho KK. Pemphigus with pemphigoid-like presentation, associated with squamous cell carcinoma of the tongue. Australas J Dermatol 2000;41:178–80. https://doi.org/10.1046/j.1440-0960.2000.00434.x
6. Anhalt GJ. Making sense of antigens and antibodies in pemphigus. Jam Acad Dermatol 1999;40:763-6. 10.1016/s0190-9622(99)70161-1
2. Anhalt GJ, Kim SC, Stanley JR et al. Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med. 1990;323:1729–1735. 10.1056/NEJM199012203232503
3. Lee SE, Kim SC. Paraneoplastic pemphigus. Dermatol Sin 2010;28:1–14. 10.23937/2469-5750/1510046
4. Kaplan I, Hodak E, Ackerman L, et al. Neoplasms associated with paraneoplastic pemphigus: A review with emphasis on nonhematologic malignancy and oral mucosal manifestations. Oral Oncol 2004;40:553–62. 10.1016/j.oraloncology.2003.09.020
5. Wong KC, Ho KK. Pemphigus with pemphigoid-like presentation, associated with squamous cell carcinoma of the tongue. Australas J Dermatol 2000;41:178–80. https://doi.org/10.1046/j.1440-0960.2000.00434.x
6. Anhalt GJ. Making sense of antigens and antibodies in pemphigus. Jam Acad Dermatol 1999;40:763-6. 10.1016/s0190-9622(99)70161-1
| Files | ||
| Issue | Vol 57, No 10 (2019) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/acta.v57i10.3253 | |
| Keywords | ||
| Paraneoplastic pemphigus Pharynx Squamous cell carcinoma | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Saalim M, Sansare K, Karjodkar F, Rahman B, Sharma S. Oral Paraneoplastic Pemphigus and Pharyngeal Squamous Cell Carcinoma: A Rare Case Report and Review of Literature. Acta Med Iran. 2020;57(10):621-623.
