Vertebral Fractures Due to Metastatic Tumors: A Case Report
-
Susan Mohamadi
,
Morteza Abouzaripour
,
Nastaran Hesam Shariati
,
Fardin Fathi
,
Mohammad Sadegh Gholami Farashah
,
Mohammad Bakhtiar Hesam Shariati
Abstract
Metastasis is responsible for most cancer-related morbidity and mortality. In principle, metastasis is the spread of cancer from the primary site to distant tissues. Pathological consistency may be compromised during metastasis. We report the case of a 55-year-old man with MRI images of the dorsal spine showing the effects of a fifth dorsal collapse. He was referred to our hospital because of back pain, imbalance, inability to walk, and weakness of the lower limb. The histological features of bone tumors were corresponding with cell carcinoma, and bone damage was considered metastatic from a site in the lung. His general situation gently diminished, and He died during radiotherapy.
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11. Ferlay J, Parkin D, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81.
12. Yin JJ, Pollock CB, Kelly K. Mechanisms of cancer metastasis to the bone. Cell Res 2005;15:57-62.
13. Miyazaki T, Kohno S, Sakamoto A, Komori K, Kumagae K, Hara K, et al. Two cases of lung carcinoma with osteoplastic bone metastasis. Intern Med 1993;32:416-20.
14. Oyewumi MO, Alazizi A, Wehrung D, Manochakian R, Safadi FF. Emerging lung cancer therapeutic targets based on the pathogenesis of bone metastases. Int J Cell Biol 2014;2014:236246.
15. Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-64.
16. Hoskin P, Yarnold J, Roos D, Bentzen S. Radiotherapy for bone metastases. Clin Oncol 2001;13:88-90.
17. Farashah MSG, Shariati NH, Asghari R, Mohamadi S, Dolatkhah MA, Shariati MBH. Pulmonary Sequestration: A Case Report. Acta Med Iran 2019;57:398-401.
2. Coleman RE. Skeletal complications of malignancy. Cancer 1997;80:1588-94.
3. Kanis J. Bone and cancer: pathophysiology and treatment of metastases. Bone 1995;17:S101-5.
4. Kosteva J, Langer C. Skeletal metastases of non-small cell lung cancer: advances in diagnosis and treatment. Lung Cancer Principles and Practices Philadelphia, PA: Lippincott Williams and Williams, 2003:1-14.
5. Coleman R. Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 2001;27:165-76.
6. Jensen AØ, Jacobsen JB, Nørgaard M, Yong M, Fryzek JP, Sørensen HT. Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark. BMC cancer 2011;11:29.
7. Ali Mohammed Hammamy R, Farooqui K, Ghadban W. Sclerotic Bone Metastasis in Pulmonary Adenocarcinoma. Case rep med 2018;2018:1-5.
8. Beckles MA, Spiro SG, Colice GL, Rudd RM. Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes. Chest 2003;123:97S-104.
9. Qaiyum M, Tyrrell P, McCall I, Cassar-Pullicino V. MRI detection of unsuspected vertebral injury in acute spinal trauma: incidence and significance. Skeletal Radiol 2001;30:299-304.
10. Ortiz, A. and S.-H. Lin. Osteolytic and osteoblastic bone metastases: two extremes of the same spectrum?, Recent Results Cancer Res 2012;192:225-33.
11. Ferlay J, Parkin D, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81.
12. Yin JJ, Pollock CB, Kelly K. Mechanisms of cancer metastasis to the bone. Cell Res 2005;15:57-62.
13. Miyazaki T, Kohno S, Sakamoto A, Komori K, Kumagae K, Hara K, et al. Two cases of lung carcinoma with osteoplastic bone metastasis. Intern Med 1993;32:416-20.
14. Oyewumi MO, Alazizi A, Wehrung D, Manochakian R, Safadi FF. Emerging lung cancer therapeutic targets based on the pathogenesis of bone metastases. Int J Cell Biol 2014;2014:236246.
15. Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-64.
16. Hoskin P, Yarnold J, Roos D, Bentzen S. Radiotherapy for bone metastases. Clin Oncol 2001;13:88-90.
17. Farashah MSG, Shariati NH, Asghari R, Mohamadi S, Dolatkhah MA, Shariati MBH. Pulmonary Sequestration: A Case Report. Acta Med Iran 2019;57:398-401.
| Files | ||
| Issue | Vol 58, No 11 (2020) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/acta.v58i11.5149 | |
| Keywords | ||
| Metastasis Lung cancer Vertebra Thoracic | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Mohamadi S, Abouzaripour M, Hesam Shariati N, Fathi F, Gholami Farashah MS, Hesam Shariati MB. Vertebral Fractures Due to Metastatic Tumors: A Case Report. Acta Med Iran. 2021;58(11):605-607.
