The Effect of Trans-Abdominal Chorionic Villus Sampling on Fetal Heart Rate and Placental Vascular Resistance Index: A Color Doppler Ultrasound Study
,
Abstract
Fetal hemodynamic changes can occur immediately following invasive chorionic villus sampling (CVS). We decided to study the possible effect of CVS on fetal heart rate (FHR), and uteroplacental resistance index (RI) changes using color Doppler ultrasound. Thirty-five pregnant patients with a gestational age of more than 12 weeks were included. Trans-abdominal CVS was done to assess the possibility of thalassemia. Before and after the CVS, color Doppler ultrasound was done to measure FHR and uteroplacental RI. Mean (SD) values for FHR before and after the CVS were 175.22 (±9) and 173.62 (±9.94) beats per minute, respectively; P=0.18. Mean (SD) uteroplacental RI before the CVS was 0.79 (0.07) which significantly increased to 0.82 (0.08); P=0.03. We observed a significant increase in resistance of blood flow in placental circulation after CVS. However, no significant change was observed regarding FHR after CVS.
1. Mujezinovic F, Alfirevic Z. Procedure-related complications of amniocentesis and chorionic villous sampling: a systematic review. Obstet Gynecol 2007;110:687-94.
2. Farshchian N, Hajsafarali M, Farshchian N, Bahrami Kamangar P. Correlation Between Transabdominal Chorionic Villus Sampling and Fetal Distress With Color Doppler Sonography. Acta Med Iran 2019;57:720-4.
3. Tabor A, Vestergaard CH, Lidegaard O. Fetal loss rate after chorionic villus sampling and amniocentesis: an 11-year national registry study. Ultrasound Obstet Gynecol 2009;34:19-24.
4. Sotiriadis A, Eleftheriades M, Chatzinikolaou F, Chatzistamatiou K, Assimakopoulos E, Chasiakos D. Fetal growth impairment after first-trimester chorionic villus sampling: a case-control study. J Matern Fetal Neonatal Med 2016;29:1731-5.
5. Akolekar R, Bower S, Flack N, Bilardo CM, Nicolaides KH. Prediction of miscarriage and stillbirth at 11-13 weeks and the contribution of chorionic villus sampling. Prenat Diagn 2011;31:38-45.
6. Wax JR, Cartin A, Chard R, Carpenter M, Pinette MG. First trimester transabdominal chorionic villus sampling--does the needle matter? J Clin Ultrasound 2012;40:385-8.
7. Akhlaghpoor S, Hosseinipoor T. The effect of chorionic villus sampling on fetal heart rate. Fetal Diagn Ther 2005;20:116-20.
8. Chung DY, Sim YB, Park KT, Yi SH, Shin JC, Kim SP. Spectral analysis of fetal heart rate variability as a predictor of intrapartum fetal distress. Int J Gynaecol Obstet 2001;73:109-16.
9. Martinez JM, Comas C, Ojuel J, Borrell A, Puerto B, Fortuny A. Immediate changes in umbilical blood flow after transcervical chorionic villus sampling performed by biopsy forceps. Prenat Diagn 1996;16:223-9.
10. Wilson RD, Gibson W, Bebbington M, Walker M, Shaw D. First trimester fetal heart rate: response to chorionic villus sampling in the chromosomally normal fetus. Fetal Diagn Ther 1997;12:236-40.
11. Nagar T, Sharma D, Choudhary M, Khoiwal S, Nagar RP, Pandita A. The Role of Uterine and Umbilical Arterial Doppler in High-risk Pregnancy: A Prospective Observational Study from India. Clin Med Insights Reprod Health 2015;9:1-5.
12. Ebrashy A, Azmy O, Ibrahim M, Waly M, Edris A. Middle cerebral/umbilical artery resistance index ratio as sensitive parameter for fetal well-being and neonatal outcome in patients with preeclampsia: case-control study. Croat Med J 2005;46:821-5.
13. Radunovic N, Kuczynski E, Kontic O, Kanjuh V, Lockwood CJ. Chorionic villus sampling significantly affects fetal cardiovascular function. J Matern Fetal Neonatal Med 2007;20:285-8.
14. Kofinas AD, D'Amico K, McGuiness T, Clay D, King K. Transabdominal chorionic villus sampling at 9.5-12 weeks' gestation. Placental vascular resistance and fetal cardiovascular responses. J Reprod Med 1995;40:453-7.
15. Zoppini C, Ludomirsky A, Godmilow L, Weiner S, Maislin G, Donnenfeld AE. Acute hemodynamic effects induced by chorionic villus sampling: a preliminary investigation. Am J Obstet Gynecol 1993;169:902-7.
2. Farshchian N, Hajsafarali M, Farshchian N, Bahrami Kamangar P. Correlation Between Transabdominal Chorionic Villus Sampling and Fetal Distress With Color Doppler Sonography. Acta Med Iran 2019;57:720-4.
3. Tabor A, Vestergaard CH, Lidegaard O. Fetal loss rate after chorionic villus sampling and amniocentesis: an 11-year national registry study. Ultrasound Obstet Gynecol 2009;34:19-24.
4. Sotiriadis A, Eleftheriades M, Chatzinikolaou F, Chatzistamatiou K, Assimakopoulos E, Chasiakos D. Fetal growth impairment after first-trimester chorionic villus sampling: a case-control study. J Matern Fetal Neonatal Med 2016;29:1731-5.
5. Akolekar R, Bower S, Flack N, Bilardo CM, Nicolaides KH. Prediction of miscarriage and stillbirth at 11-13 weeks and the contribution of chorionic villus sampling. Prenat Diagn 2011;31:38-45.
6. Wax JR, Cartin A, Chard R, Carpenter M, Pinette MG. First trimester transabdominal chorionic villus sampling--does the needle matter? J Clin Ultrasound 2012;40:385-8.
7. Akhlaghpoor S, Hosseinipoor T. The effect of chorionic villus sampling on fetal heart rate. Fetal Diagn Ther 2005;20:116-20.
8. Chung DY, Sim YB, Park KT, Yi SH, Shin JC, Kim SP. Spectral analysis of fetal heart rate variability as a predictor of intrapartum fetal distress. Int J Gynaecol Obstet 2001;73:109-16.
9. Martinez JM, Comas C, Ojuel J, Borrell A, Puerto B, Fortuny A. Immediate changes in umbilical blood flow after transcervical chorionic villus sampling performed by biopsy forceps. Prenat Diagn 1996;16:223-9.
10. Wilson RD, Gibson W, Bebbington M, Walker M, Shaw D. First trimester fetal heart rate: response to chorionic villus sampling in the chromosomally normal fetus. Fetal Diagn Ther 1997;12:236-40.
11. Nagar T, Sharma D, Choudhary M, Khoiwal S, Nagar RP, Pandita A. The Role of Uterine and Umbilical Arterial Doppler in High-risk Pregnancy: A Prospective Observational Study from India. Clin Med Insights Reprod Health 2015;9:1-5.
12. Ebrashy A, Azmy O, Ibrahim M, Waly M, Edris A. Middle cerebral/umbilical artery resistance index ratio as sensitive parameter for fetal well-being and neonatal outcome in patients with preeclampsia: case-control study. Croat Med J 2005;46:821-5.
13. Radunovic N, Kuczynski E, Kontic O, Kanjuh V, Lockwood CJ. Chorionic villus sampling significantly affects fetal cardiovascular function. J Matern Fetal Neonatal Med 2007;20:285-8.
14. Kofinas AD, D'Amico K, McGuiness T, Clay D, King K. Transabdominal chorionic villus sampling at 9.5-12 weeks' gestation. Placental vascular resistance and fetal cardiovascular responses. J Reprod Med 1995;40:453-7.
15. Zoppini C, Ludomirsky A, Godmilow L, Weiner S, Maislin G, Donnenfeld AE. Acute hemodynamic effects induced by chorionic villus sampling: a preliminary investigation. Am J Obstet Gynecol 1993;169:902-7.
| Files | ||
| Issue | Vol 59, No 3 (2021) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/acta.v59i3.5788 | |
| Keywords | ||
| Chorionic villus sampling Fetal heart rate Resistance index Doppler | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Farshchian N, Naleini F, Farshchian N, Kamangar P. The Effect of Trans-Abdominal Chorionic Villus Sampling on Fetal Heart Rate and Placental Vascular Resistance Index: A Color Doppler Ultrasound Study. Acta Med Iran. 2021;59(3):169-172.
