Renal Oncocytoma: A Large Tumor, Report of a Case and Review of Literature
,
Abstract
Oncocytoma is a common benign kidney tumor. The size is often less than 5 cm. Oncocytomas may be misdiagnosed in clinic, radiology and histopathology for renal cell carcinoma. Different panels of immunohistochemistry (IHC) are suggested in the renal tumors with eosinophilic granular cytoplasm including oncocytoma, chromophobe and clear renal cell carcinoma. Here we report a large oncocytoma in a 64-year-old lady, that the mimickers ruled out by IHC.
1. Dey S, Noyes SL, Uddin G, Lane BR. Palpable Abdominal Mass is a Renal Oncocytoma: Not All Large Renal Masses are Malignant. Case Rep Urol 2019;2019:6016870.
2. Abualjadayel MH, Safdar OY, Banjari MA, El Desoky S, Mokhtar GA, Azhar RA. A Rare Benign Tumor in a 14-Year-Old Girl. Case Rep Nephrol 2018;2018:1548283.
3. Balaji AR, Prakash JVS, Darlington D. Cystic renal oncocytoma mimicking renal cell carcinoma. Urol Ann 2019;11:98-101.
4. Sussman RD, Kowalczyk KJ. Giant renal oncocytoma with classic stellate scar. BMJ Case Rep 2017;2017:bcr2016218944.
5. Kolníková G, Marinová P, Gál V, Mečiarová I, Mišanko V, Rampalová J, et al. Renal oncocytoma with invasive histopathologic features- case report. Klin Onkol 2014;27:138-42.
6. Shakarchi J, Wharton I, Youssef A, Anderson P. Giant renal oncocytoma. Radiol Case Rep 2015;4:307.
7. Cheng JL, Beebe JD, Nepple KG, Zakharia Y, Mullins RF, Flamme-Wiese MJ, et al. Autoimmune retinopathy and optic neuropathy associated with enolase-positive renal oncocytoma. Am J Ophthalmol Case Rep 2018;12:55-60.
8. Badmus TA, Adesunkanmi AR, Agbakwuru CA, Salako AA, Uhunmwagho O, Eziyi AK. Giant renal oncocytoma masquerading as infiltrating renal cell carcinoma: case report and literature review. Cent Afr J Med 2006;52:16-9.
9. Geramizadeh B, Ravanshad M, Rahsaz M. Useful markers for differential diagnosis of oncocytoma, chromophobe renal cell carcinoma and conventional renal cell carcinoma. Indian J Pathol Microbiol 2008;51:167-71.
10. Zhao W, Tian B, Wu C, Peng Y, Wang H, Gu WL, et al. DOG1, cyclin D1, CK7, CD117 and vimentin are useful immunohistochemical markers in distinguishing chromophobe renal cell carcinoma from clear cell renal cell carcinoma and renal oncocytoma. Pathol Res Pract 2015;211:303-7.
11. Guo Q, Liu N, Wang F, Guo Y, Yang B, Cao Z, et al. Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new evidence from China. Virchows Arch 2021;478:449-58.
12. Omiyale A, Carton J. Renal oncocytoma with vascular and perinephric fat invasion. Ther Adv Urol 2019;11:175628721988485.
13. Maiers TJ, Wang DC, Houjaij AH, Darwish OM. Renal Oncocytoma and Retroperitoneal Ancient Schwannoma: A Benign Mimic of Metastatic Renal Cell Carcinoma. Case Rep Urol 2019;2019:2561289.
14. Knechtle B, Neuweiler J, Berchtold D. Fallbeschreibung: Renales Onkozytom und Basedow-Hyperthyreose [Case report: renal oncocytoma and Basedow hyperthyroidism]. Praxis (Bern 1994) 1994;83:1256-60.
2. Abualjadayel MH, Safdar OY, Banjari MA, El Desoky S, Mokhtar GA, Azhar RA. A Rare Benign Tumor in a 14-Year-Old Girl. Case Rep Nephrol 2018;2018:1548283.
3. Balaji AR, Prakash JVS, Darlington D. Cystic renal oncocytoma mimicking renal cell carcinoma. Urol Ann 2019;11:98-101.
4. Sussman RD, Kowalczyk KJ. Giant renal oncocytoma with classic stellate scar. BMJ Case Rep 2017;2017:bcr2016218944.
5. Kolníková G, Marinová P, Gál V, Mečiarová I, Mišanko V, Rampalová J, et al. Renal oncocytoma with invasive histopathologic features- case report. Klin Onkol 2014;27:138-42.
6. Shakarchi J, Wharton I, Youssef A, Anderson P. Giant renal oncocytoma. Radiol Case Rep 2015;4:307.
7. Cheng JL, Beebe JD, Nepple KG, Zakharia Y, Mullins RF, Flamme-Wiese MJ, et al. Autoimmune retinopathy and optic neuropathy associated with enolase-positive renal oncocytoma. Am J Ophthalmol Case Rep 2018;12:55-60.
8. Badmus TA, Adesunkanmi AR, Agbakwuru CA, Salako AA, Uhunmwagho O, Eziyi AK. Giant renal oncocytoma masquerading as infiltrating renal cell carcinoma: case report and literature review. Cent Afr J Med 2006;52:16-9.
9. Geramizadeh B, Ravanshad M, Rahsaz M. Useful markers for differential diagnosis of oncocytoma, chromophobe renal cell carcinoma and conventional renal cell carcinoma. Indian J Pathol Microbiol 2008;51:167-71.
10. Zhao W, Tian B, Wu C, Peng Y, Wang H, Gu WL, et al. DOG1, cyclin D1, CK7, CD117 and vimentin are useful immunohistochemical markers in distinguishing chromophobe renal cell carcinoma from clear cell renal cell carcinoma and renal oncocytoma. Pathol Res Pract 2015;211:303-7.
11. Guo Q, Liu N, Wang F, Guo Y, Yang B, Cao Z, et al. Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new evidence from China. Virchows Arch 2021;478:449-58.
12. Omiyale A, Carton J. Renal oncocytoma with vascular and perinephric fat invasion. Ther Adv Urol 2019;11:175628721988485.
13. Maiers TJ, Wang DC, Houjaij AH, Darwish OM. Renal Oncocytoma and Retroperitoneal Ancient Schwannoma: A Benign Mimic of Metastatic Renal Cell Carcinoma. Case Rep Urol 2019;2019:2561289.
14. Knechtle B, Neuweiler J, Berchtold D. Fallbeschreibung: Renales Onkozytom und Basedow-Hyperthyreose [Case report: renal oncocytoma and Basedow hyperthyroidism]. Praxis (Bern 1994) 1994;83:1256-60.
| Files | ||
| Issue | Vol 61 No 1 (2023) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/acta.v61i1.12128 | |
| Keywords | ||
| Renal oncocytoma Case report Large tumor | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Ramezani M, Karami K, Mohammadi K, Baharzadeh F. Renal Oncocytoma: A Large Tumor, Report of a Case and Review of Literature. Acta Med Iran. 2023;61(1):61-63.
