2023 CiteScore: 0.7
pISSN: 0044-6025
eISSN: 1735-9694
Editor-in-Chief:
Ahmadreza Dehpour, PharmD, PhD
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE).
Vol X, No 3-4 (1967)
Original Article(s)
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The tranquilizing~ effects of five phenothiazine derivates have been studied in . aaitation produced in the mice by .. . envates have been studied in injecting amphetamine. The activit.ies of these compounds were compared. Values in decreasing order were Aceprornazine, Perphenazine~, Trifluoperazr.ne, Chlorpromazine and Percoremaaszininge.order
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Three cases of hepatic coma due to acute hepatitis were treated by exchange transfusion with citrated blood. This was preformed in the first 2 cases (patients No 1 and No 2) after failing to respond to other forms of treatment, and in the last patient, who was admitted to hospital in coma, a few hours after admission. (patient No 3) Two of the 3 patients, patients 1 and 3 recovered, 1 died, (patient No 2) although 2 successive exchange transfusions alleviated coma to some degree.
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The following results were obtained after a comparison of the blood formula percentages of irradiated and non-irradiated hemopoietic cells in the livers of the embryonic mice.-
1. The radiosensitivity is higher for white cells than for red ones.
2. The most sensitive cells among the white cells are the megaloblast, followed by myeloblastes, lyrnphoblastes and myelocytes.
3. For the red cell, the most sensitive are the basophyric normoblasts, followed by chrornatophylic normoblasts and finally the nucleoteads cells.
4. The only resistant cells among the white cells are the polymorphonuclear cells. These four points have been demonstrated with some accuracy. It has been shown that the radiosensitivity for cells which are capable to divide and differentiate is higher than for the cells which lack these Properties.
