Acta Medica Iranica 2017. 55(1):6-23.

Multipotent Stem Cell and Current Application
Aligholi Sobhani, Neda Khanlarkhani, Maryam Baazm, Farzaneh Mohammadzadeh, Atefeh Najafi, Shayesteh Mehdinejadiani, Fereydoon Sargolzaei Aval


Stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. Stem cells can be classified into two main types based on their source of origin: Embryonic and Adult stem cells. Stem cells also classified based on the range of differentiation potentials into Totipotent, Pluripotent, Multipotent, and Unipotent. Multipotent stem cells have the ability to differentiate into all cell types within one particular lineage. There are plentiful advantages and usages for multipotent stem cells. Multipotent Stem cells act as a significant key in procedure of development, tissue repair, and protection. Multipotent Stem cells have been applying in treatment of different disorders such as spinal cord injury, bone fracture, autoimmune diseases, rheumatoid arthritis, hematopoietic defects, and fertility preservation.


Multipotent; Stem cell; Fertility; Preservation; Regenerative medicine

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