Acta Medica Iranica 2018. 56(3):196-203.

The French Maritime Pine Bark Extract Reduce Metabolic Syndrome Risk and Improve Body Composition in Obesity: A New Clinical Approach
Mohsen Sedighiyan, Mina Abdolahi, Ehsaneh Taheri, Mostafa Qorbani, Parisa Omidian, Saeed Hosseini


Metabolic syndrome is a cluster of conditions which enhance the risk of metabolic and cardiovascular diseases such as diabetes mellitus, dyslipidemia, or hypertension. Obesity plays a pivotal role in the pathogenesis of metabolic syndrome. French maritime Pine bark extract (PBE) in addition to its antioxidant properties, has protective effects on metabolic syndrome component through several mechanisms. At present, there are few data on the net impact of PBE on metabolic syndrome factors in obesity. This trial report the results of 2-month period supplementation of 38 obese women received weight loss diet and PBE (150mg/day) or placebo. The metabolic syndrome parameters and body composition were assessed at the beginning and end of the study. The results showed PBE has significant protective effects on metabolic syndrome factors including central obesity, TG, HDL, BP and FBS (P<0.05), decrease metabolic syndrome risk in obesity and improve body composition. Thus, The PBE is considered as a new approach to obesity and metabolic syndrome prevention.


Pine bark extract, Weight loss, Obesity, Metabolic syndrome, Body composition

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