Evaluation of the Effectiveness of Using Pulse Dose Radiofrequency for Treatment of Trigeminal Neuralgia
Abstract
Trigeminal neuralgia has an incidence of 4-13 per 100000 people per year. The incidence of this disease increases in the elderly, and it is known to cause severe shock-like pain. Pharmacological therapy is the first-line treatment of trigeminal neuralgia. If pharmacological therapy fails, then different procedures are available. Pulse-dose radiofrequency is one such procedure. In this study, we evaluated Pulse dose radiofrequency's efficacy as a method in which pulse amplitude and width are considered essential variables. This research was conducted as a cross-sectional study on trigeminal neuralgia patients referred to the pain clinic of Amir A’lam Hospital in 2020. Conservative therapy has failed; therefore, the clinician decided to use pulse dose radiofrequency to reduce their pain. Among the 29 patients registered during this period, 15 (51.8%) were women and 14 (48.3%) were men. The mean (±SD) age of the patient was 57.07(±14.26) years. The tow route was interrupted in 7 (24.1%) patients. A significant difference was observed between the pain scores before and after the operation (P<0.001). Pulse-dose radiofrequency is a safe and effective therapy for treating trigeminal neuralgia and can be considered a new way to develop the pulse radiofrequency method.
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2. MacDonald BK, Cockerell OC, Sander JW, Shorvon SD. The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain 2000;123:665-76.
3. Sabourin V, Lavergne P, Mazza J, Head J, Al-Saiegh F, Stefanelli T, et al. Internal Neurolysis for the Treatment of Trigeminal Neuralgia: A Systematic Review. World Neurosurg 2022:158:e829-42.
4. Erdine S, Ozyalcin NS, Cimen A, Celik M, Talu GK, Disci R. Comparison of pulsed radiofrequency with conventional radiofrequency in the treatment of idiopathic trigeminal neuralgia. Eur J Pain 2007;11:309-13.
5. Shah RJ, Dixon B, Padalia D. Sphenopalatine Ganglion Radiofrequency Thermocoagulation. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.
6. Wu H, Zhou J, Chen J, Gu Y, Shi L, Ni H. Therapeutic efficacy and safety of radiofrequency ablation for the treatment of trigeminal neuralgia: a systematic review and meta-analysis. J Pain Res 2019;12:423-41.
7. Ojango C, Raguso M, Fiori R, Masala S. Pulse-dose radiofrequency treatment in pain management-initial experience. Skeletal Radiol 2018;47:609-18.
8. Yao P, Tao Hong, Wang ZB, Ma JM, Zhu YQ, Li HX, et al. Treatment of bilateral idiopathic trigeminal neuralgia by radiofrequency thermocoagulation at different temperatures. Medicine 2016;95:e4274.
9. Wu H, Zhou J, Chen J, Gu Y, Shi L, Ni H. Therapeutic efficacy and safety of radiofrequency ablation for the treatment of trigeminal neuralgia: a systematic review and meta-analysis. J Pain Res 2019;12:423-41.
10. Bick SKB, Eskandar EN. Surgical Treatment of Trigeminal Neuralgia. Neurosurg Clin N Am 2017;28:429-38.
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12. Tyler-Kabara EC, Kassam AB, Horowitz MH, Urgo L, Hadjipanayis C, Levy EI, et al., Predictors of outcome in surgically managed patients with typical and atypical trigeminal neuralgia: comparison of results following microvascular decompression. J Neurosurg 2002;96:527-31.
13. Bartindale M, Kircher M, Adams W, Balasubramanian N, Liles J, Bell J, et al., Hearing Loss following Posterior Fossa Microvascular Decompression: A Systematic Review. Otolaryngol Head Neck Surg 2018;158:62-75.
14. Lee S, Park SK, Joo BE, Lee JA, Park K. Vascular Complications in Microvascular Decompression: A Survey of 4000 Operations. World Neurosurg 2019;130:e577-82.
15. Xia L, Zhong J, Zhu J, Wang YN, Dou NN, Liu MX, et al. Effectiveness and safety of microvascular decompression surgery for treatment of trigeminal neuralgia: a systematic review. J Craniofac Surg 2014;25:1413-7.
16. Lopez BC, Hamlyn PJ, Zakrzewska JM. Systematic review of ablative neurosurgical techniques for the treatment of trigeminal neuralgia. Neurosurgery 2004;54:973-82; discussion 982-3.
17. Higuchi Y, Nashold Jr BS, Sluijter M, Cosman E, Pearlstein RD. Exposure of the dorsal root ganglion in rats to pulsed radiofrequency currents activates dorsal horn lamina I and II neurons. Neurosurgery 2002;50:850-5; discussion 856.
18. Zundert JV, Brabant S, de Kelft EV, Vercruyssen A, Van Buyten JP. Pulsed radiofrequency treatment of the Gasserian ganglion in patients with idiopathic trigeminal neuralgia. Pain 2003;104:449-52.
19. Singh S, Verma R, Kumar M, Rastogi V, Bogra J. Experience with conventional radiofrequency thermorhizotomy in patients with failed medical management for trigeminal neuralgia. Korean J Pain 2014;27:260-5.
20. Agarwal A, Rastogi S, Bansal M, Kumar S, Malviya D, Thacker AK. Radiofrequency Treatment of Idiopathic Trigeminal Neuralgia (Conventional vs. Pulsed): A Prospective Randomized Control Study. Anesth Essays Res 2021;15:14-9.
21. Huibin Q, Jianxing L, Guangyu H, Dianen F. The treatment of first division idiopathic trigeminal neuralgia with radiofrequency thermocoagulation of the peripheral branches compared to conventional radiofrequency. J Clin Neurosci 2009;16:1425-9.
22. Hong T, Ding Y, Yao P. Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia. Biochem Res Int 2020;2020:3854284.
23. Li X, Ni J, Yang L, Wu B, He M, Zhang X, et al. A prospective study of Gasserian ganglion pulsed radiofrequency combined with continuous radiofrequency for the treatment of trigeminal neuralgia. J Clin Neurosci 2012;19:824-8.
24. Fouad W. Management of trigeminal neuralgia by radiofrequency thermocoagulation. Alexandria J Med 2011;47:79-86.
25. Zhao WX, Wang Q, He MW, Yang LQ, Wu BS, Ni JX. Radiofrequency thermocoagulation combined with pulsed radiofrequency helps relieve postoperative complications of trigeminal neuralgia. Genet Mol Res 2015;14:7616-23.
26. Yao P, Hong T, Zhu YQ, Li HX, Wang ZB, Ding YY, et al. Efficacy and safety of continuous radiofrequency thermocoagulation plus pulsed radiofrequency for treatment of V1 trigeminal neuralgia: A prospective cohort study. Medicine (Baltimore) 2016;95:e5247.
27. Yao P, Deng YY, Hong T, Wang ZB, Ma JM, Zhu YQ, et al. Radiofrequency thermocoagulation for V2/V3 idiopathic trigeminal neuralgia: effect of treatment temperatures on long-term clinical outcomes: A Cohort Study. Medicine (Baltimore) 2016;95:e4019.
28. Liu P, Zhong W, Liao C, Yang M, Zhang W. The Role of Percutaneous Radiofrequency Thermocoagulation for Persistent or Recurrent Trigeminal Neuralgia After Surgery. J Craniofac Surg 2016;27:e752-5.
29. Zheng S, Wu B, Zhao Y, Wang X, Li X, Yang L, et al. Masticatory Muscles Dysfunction after CT-guided Percutaneous Trigeminal Radiofrequency Thermocoagulation for Trigeminal Neuralgia: A Detailed Analysis. Pain Pract 2015;15:712-9.
2. MacDonald BK, Cockerell OC, Sander JW, Shorvon SD. The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain 2000;123:665-76.
3. Sabourin V, Lavergne P, Mazza J, Head J, Al-Saiegh F, Stefanelli T, et al. Internal Neurolysis for the Treatment of Trigeminal Neuralgia: A Systematic Review. World Neurosurg 2022:158:e829-42.
4. Erdine S, Ozyalcin NS, Cimen A, Celik M, Talu GK, Disci R. Comparison of pulsed radiofrequency with conventional radiofrequency in the treatment of idiopathic trigeminal neuralgia. Eur J Pain 2007;11:309-13.
5. Shah RJ, Dixon B, Padalia D. Sphenopalatine Ganglion Radiofrequency Thermocoagulation. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.
6. Wu H, Zhou J, Chen J, Gu Y, Shi L, Ni H. Therapeutic efficacy and safety of radiofrequency ablation for the treatment of trigeminal neuralgia: a systematic review and meta-analysis. J Pain Res 2019;12:423-41.
7. Ojango C, Raguso M, Fiori R, Masala S. Pulse-dose radiofrequency treatment in pain management-initial experience. Skeletal Radiol 2018;47:609-18.
8. Yao P, Tao Hong, Wang ZB, Ma JM, Zhu YQ, Li HX, et al. Treatment of bilateral idiopathic trigeminal neuralgia by radiofrequency thermocoagulation at different temperatures. Medicine 2016;95:e4274.
9. Wu H, Zhou J, Chen J, Gu Y, Shi L, Ni H. Therapeutic efficacy and safety of radiofrequency ablation for the treatment of trigeminal neuralgia: a systematic review and meta-analysis. J Pain Res 2019;12:423-41.
10. Bick SKB, Eskandar EN. Surgical Treatment of Trigeminal Neuralgia. Neurosurg Clin N Am 2017;28:429-38.
11. Tai AX, Nayar VV. Update on Trigeminal Neuralgia. Curr Treat Options Neurol 2019;21:42.
12. Tyler-Kabara EC, Kassam AB, Horowitz MH, Urgo L, Hadjipanayis C, Levy EI, et al., Predictors of outcome in surgically managed patients with typical and atypical trigeminal neuralgia: comparison of results following microvascular decompression. J Neurosurg 2002;96:527-31.
13. Bartindale M, Kircher M, Adams W, Balasubramanian N, Liles J, Bell J, et al., Hearing Loss following Posterior Fossa Microvascular Decompression: A Systematic Review. Otolaryngol Head Neck Surg 2018;158:62-75.
14. Lee S, Park SK, Joo BE, Lee JA, Park K. Vascular Complications in Microvascular Decompression: A Survey of 4000 Operations. World Neurosurg 2019;130:e577-82.
15. Xia L, Zhong J, Zhu J, Wang YN, Dou NN, Liu MX, et al. Effectiveness and safety of microvascular decompression surgery for treatment of trigeminal neuralgia: a systematic review. J Craniofac Surg 2014;25:1413-7.
16. Lopez BC, Hamlyn PJ, Zakrzewska JM. Systematic review of ablative neurosurgical techniques for the treatment of trigeminal neuralgia. Neurosurgery 2004;54:973-82; discussion 982-3.
17. Higuchi Y, Nashold Jr BS, Sluijter M, Cosman E, Pearlstein RD. Exposure of the dorsal root ganglion in rats to pulsed radiofrequency currents activates dorsal horn lamina I and II neurons. Neurosurgery 2002;50:850-5; discussion 856.
18. Zundert JV, Brabant S, de Kelft EV, Vercruyssen A, Van Buyten JP. Pulsed radiofrequency treatment of the Gasserian ganglion in patients with idiopathic trigeminal neuralgia. Pain 2003;104:449-52.
19. Singh S, Verma R, Kumar M, Rastogi V, Bogra J. Experience with conventional radiofrequency thermorhizotomy in patients with failed medical management for trigeminal neuralgia. Korean J Pain 2014;27:260-5.
20. Agarwal A, Rastogi S, Bansal M, Kumar S, Malviya D, Thacker AK. Radiofrequency Treatment of Idiopathic Trigeminal Neuralgia (Conventional vs. Pulsed): A Prospective Randomized Control Study. Anesth Essays Res 2021;15:14-9.
21. Huibin Q, Jianxing L, Guangyu H, Dianen F. The treatment of first division idiopathic trigeminal neuralgia with radiofrequency thermocoagulation of the peripheral branches compared to conventional radiofrequency. J Clin Neurosci 2009;16:1425-9.
22. Hong T, Ding Y, Yao P. Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia. Biochem Res Int 2020;2020:3854284.
23. Li X, Ni J, Yang L, Wu B, He M, Zhang X, et al. A prospective study of Gasserian ganglion pulsed radiofrequency combined with continuous radiofrequency for the treatment of trigeminal neuralgia. J Clin Neurosci 2012;19:824-8.
24. Fouad W. Management of trigeminal neuralgia by radiofrequency thermocoagulation. Alexandria J Med 2011;47:79-86.
25. Zhao WX, Wang Q, He MW, Yang LQ, Wu BS, Ni JX. Radiofrequency thermocoagulation combined with pulsed radiofrequency helps relieve postoperative complications of trigeminal neuralgia. Genet Mol Res 2015;14:7616-23.
26. Yao P, Hong T, Zhu YQ, Li HX, Wang ZB, Ding YY, et al. Efficacy and safety of continuous radiofrequency thermocoagulation plus pulsed radiofrequency for treatment of V1 trigeminal neuralgia: A prospective cohort study. Medicine (Baltimore) 2016;95:e5247.
27. Yao P, Deng YY, Hong T, Wang ZB, Ma JM, Zhu YQ, et al. Radiofrequency thermocoagulation for V2/V3 idiopathic trigeminal neuralgia: effect of treatment temperatures on long-term clinical outcomes: A Cohort Study. Medicine (Baltimore) 2016;95:e4019.
28. Liu P, Zhong W, Liao C, Yang M, Zhang W. The Role of Percutaneous Radiofrequency Thermocoagulation for Persistent or Recurrent Trigeminal Neuralgia After Surgery. J Craniofac Surg 2016;27:e752-5.
29. Zheng S, Wu B, Zhao Y, Wang X, Li X, Yang L, et al. Masticatory Muscles Dysfunction after CT-guided Percutaneous Trigeminal Radiofrequency Thermocoagulation for Trigeminal Neuralgia: A Detailed Analysis. Pain Pract 2015;15:712-9.
| Files | ||
| Issue | Vol 61 No 9 (2023) | |
| Section | Articles | |
| DOI | https://doi.org/10.18502/acta.v61i9.15291 | |
| Keywords | ||
| Trigeminal neuralgia Pulse dose radiofrequency | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Sheikhhosseini S, Nazemian Yazdi NA. Evaluation of the Effectiveness of Using Pulse Dose Radiofrequency for Treatment of Trigeminal Neuralgia. Acta Med Iran. 2024;61(9):578-581.
