Original Articles

Determination Infertility-Related Stress Among Women Attending an Infertility Center: A Cross-Sectional Study

Abstract

Infertility is a difficult experience that can greatly impact a woman's mental, emotional, and thus, physical wellbeing. The study aimed to assess the infertility-related stress among women attending an infertility center and the associated socio-demographic characteristics. A cross-sectional descriptive study was conducted at Kamal Al-Samarrai Hospital for Fertility and Infertility in Baghdad from November 2023 to November 2024 to investigate infertility-related stress among 385 women diagnosed with infertility. Data were collected through interviews using the modified infertility-related stress questionnaire, and validity and reliability were established through expert ratings and a pilot study. Statistical analysis was performed using IBM SPSS 20.0, employing techniques such as Pearson correlation, Regression, and Kruskal-Wallis assessments. The results indicate that the majority (97.1%) reported moderate infertility-related stress, with an average stress rating of 92.96. An inverse relationship was observed between age and infertility-related stress, indicating that stress tends to decrease with age (r= -0.151, P=0.003). Additionally, a statistical analysis showed that infertility-related stress levels differed significantly based on education level (P=0.010) and monthly income (P=0.016). The study found mild stress among women with infertility, especially younger, less educated, and lower-income women. The study recommends less expensive counseling, advanced fertility resources, and public awareness to reduce stigma and help affected women improve their health.

1. Hazlina NH, Norhayati MN, Bahari IS, Arif NA. Worldwide prevalence, risk factors and psychological impact of infertility among women: a systematic review and meta-analysis. BMJ Open 2022;12:e057132.
2. Woods BM, Patrician PA, Fazeli PL, Ladores S. Infertility‐related stress: A concept analysis. Nurs Forum 2022;57:437-45.
3. Idugboe MI, Umeh NJ, Adewara OR, Jarjusey S, Okobi OE, Adetifa O. The Psychological Impact of Infertility on Couples: Exploring the Role of Support Systems and Coping Mechanisms. Int J Res Rep Gynaecol 2024;7:88-98.
4. Radhi MM, Al-Eqabi QA, Hindi NK. Rehabilitation problems of people with motor disabilities at Babylon center for rehabilitation of the disabled. Med J Babylon 2023;20:838-43.
5. Assaysh-Öberg S, Borneskog C, Ternström E. Women's experience of infertility & treatment–A silent grief and failed care and support. Sex Reprod Healthc 2023;37:100879.
6. Yurci A. The impact of psychological factors on in vitro fertilization (IVF) outcomes: a comprehensive review. J Compr Surg 2024;2:35-8.
7. Galst JP. The elusive connection between stress and infertility: A research review with clinical implications. J Psychother Integration 2018;28:1.
8. Sambasivam I, Jennifer HG. Understanding the experiences of helplessness, fatigue and coping strategies among women seeking treatment for infertility–A qualitative study. J Educ Health Promot 2023:12:309.
9. Szkodziak F, Krzyżanowski J, Szkodziak P. Psychological aspects of infertility. A systematic review. J Int Med Res 2020;48:300060520932403.
10. Bala R, Singh V, Rajender S, Singh K. Environment, lifestyle, and female infertility. Reprod Sci 2021;28:617-38.
11. Vioreanu AM. The psychological impact of infertility. Directions for the development of interventions. Mental Health: Glob Chall 2021;4:22-37.
12. Ali B, Touseef M, Niaz U, Sarwar S, Iqbal S, Idrees M, et al. Silent Suffering: A Qualitative Study On The Impact Of Infertility On The Social And Psychological Health Of Women In District Faisalabad, Pakistan, And Its Socio-Cultural Factors. J Positive Sch Psychol 2023;7:330-49.
13. Collins ME. The impact of infertility on daily occupations and roles. J Reprod Infertil 2019;20:24.
14. Gameiro S, El Refaie E, de Guevara BB, Payson A. Women from diverse minority ethnic or religious backgrounds desire more infertility education and more culturally and personally sensitive fertility care. Hum Reprod 2019;34:1735-45.
15. Charan J, Biswas T. How to calculate sample size for different study designs in medical research? Indian J Psychol Med 2013;35:121-6.
16. Newton CR, Sherrard W, Glavac I. The Fertility Problem Inventory: measuring perceived infertility-related stress. Fertil Steril 1999;72:54-62.
17. Iordăchescu DA, Paica CI, Boca AE, Gică C, Panaitescu AM, Peltecu G, Veduță A, Gică N. Anxiety, difficulties, and coping of infertile women. Healthcare (Basel) 2021;9:466.
18. Palomba S, Daolio J, Romeo S, Battaglia FA, Marci R, La Sala GB. Lifestyle and fertility: the influence of stress and quality of life on female fertility. Reprod Biol Endocrinol 2018;16:113.
19. Ikemoto Y, Kuroda K, Endo M, Tanaka A, Sugiyama R, Nakagawa K, et al. Analysis of severe psychological stressors in women during fertility treatment: Japan-Female Employment and Mental health in Assisted reproductive technology (J-FEMA) study. Arch Gynecol Obstet 2021;304:253-61.
20. Swift AD. Relationships Between Infertility-related Stress, Hair Cortisol, Coping, and Quality of Life in US Women Undergoing Infertility Treatments. J Obstet Gynecol Neonatal Nurs 2021;50:275-88.
21. Renzi A, Di Trani M, Solano L, Minutolo E, Tambelli R. Alexithymia, infertility‐related stress and quality of life in women undergoing an Assisted Reproductive Treatment. Stress Health 2020;36:654-62.
22. Roozitalab S, Rahimzadeh M, Mirmajidi SR, Ataee M, Saeieh SE. The relationship between infertility, stress, and quality of life with posttraumatic stress disorder in infertile women. J Reprod Infertil 2021;22:282-8.
23. Malih Radhi M, Juma Elywy G, Abbas Khyoosh Al-Eqabi Q. Burdens Among Wives of Disabled People in the Light of Some Social Variables. Iranian Rehabil J 2023;21:473-84.
24. Elywy GJ, Radhi MM, AlEqabi QA. Relationship between social support and self-hardiness among breast cancer women in Nasiriyah, Iraq. J Pakistan Med Assoc 2023;73:S9-14.
25. Li Y, Zhang X, Shi M, Guo S, Wang L. Resilience acts as a moderator in the relationship between infertility-related stress and fertility quality of life among women with infertility: a cross-sectional study. Health Qual Life Outcomes 2019;17:1-9.
26. Brochu F, Robins S, Miner SA, Grunberg PH, Chan P, Lo K, et al. Searching the internet for infertility information: a survey of patient needs and preferences. J Med Internet Res 2019;21:e15132.
27. Zurlo MC, Cattaneo Della Volta MF, Vallone F. Predictors of quality of life and psychological health in infertile couples: the moderating role of duration of infertility. Qual Life Res 2018;27:945-54.
28. Yasir AA, Qassim WJ, Radhi MM. Assessment the feeling of psychological loneliness among wives of martyrs in the light of some social variables in Babylon Governorate/Iraq. J Pharm Sci Res 2018;10:40-4.
29. Umoh NR. Socioeconomic Status and Women's Mental Health and Wellbeing in Male-Factor Infertility Marital Circumstances: A Scoping Review. medRxiv 2022.
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IssueVol 63 No 3 (2025) QRcode
SectionOriginal Articles
DOI https://doi.org/10.18502/acta.v63i3.19715
Keywords
Infertility Infertility-related stress Reproductive health Psychological adjustment

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How to Cite
1.
Sheehan Rasein LS, K Jihad S, AL Rubayae B. Determination Infertility-Related Stress Among Women Attending an Infertility Center: A Cross-Sectional Study. Acta Med Iran. 2025;63(3):159-164.