Peutz-Jeghers Syndrome Report of one case associated with Gastrointestin Carcinoma

Abstract

The peutz-Jeghers syndrome is characterized by an association of gastrointestinal polyposis with rnelain spots on oral mucosa, lips, and skin. This symdrorne is inherited as a simple mendelian autosomal dominant trait. Intussusception is by far the most common complication. Although these polyps are widely regarded as hamartomas and rarely undergo malignant change, they have been reported to be associated with carcinoma of gastrointestin and ovary.
In the case reported here, the cancer developed from hamartomatous polyps.