A Woman with Nasal Mass and Epistaxis: An Unusual Presentation of Leprosy
,
Abstract
Leprosy is an infectious and non-fatal disease that mainly involved skin and peripheral nervous system and caused by Mycobacterium Lepra. This case is a 41-year-old woman with intermittent nasal bleeding and a mass (1.5×2.5 cm) in the right side of lateral nasal wall and a (1×1 cm) mass on septum in the left side of the nose. Considering the probability of intranasal tumor, endoscopic biopsy for histopathologic examination had been done and the result confirmed the diagnosis of leprosy. After unexpected proving of pathologic leprelepromatose, the patient put under 3-drug- treatment.
Elder D, Elenitsas R, Jaworsky C, Johnson B Jr, editors. Lever's Histopathology of the Skin. 8th ed. Philadelphia: Lippincott-Raven; 1997. p. 477-88.
Hartzell JD, Zapor M, Peng S, Straight T. Leprosy: a caseseries and review. South Med J 2004;97(12):1252-6.
Jacobson RR, Krahenbuhl JL. Leprosy. Lancet 1999;353(9153):655-60.
Marlowe SN, Lockwood DN. Update on leprosy. Hosp Med 2001;62(8):471-6.
Ridley DS, Job CK. The pathology of leprosy. In: Hastings RC, editor. Leprosy. New York: Churchill Livingstone; 1985. p. 129.
Gelber RH. Leprosy (Hansen's disease). In: Kasper DL, Braunwald E, Hauser SL, Longo DL, Jameson JL, Fauci AS, editors. Harrison's Principles of Internal Medicine. 16thed. New York: McGrow-Hill; 2005. p. 966-77.
Barton RP. A clinical study of the nose in lepromatous leprosy. Lepr Rev 1974;45(2):135-44.
Meyers WM. Leprosy. Dermatol Clin 1992;10(1):73-96.
Farshchian M, Kheirandish A. Clinico-pathological study of 12 cases of patients with leprosy admitted to Sina Hospital, Hamadan, Iran, from 1991 to 2000. Int J Dermatol 2004;43(12):906-10.
Lockwood DNJ, Bryceson AMD. Leprosy. In: Champion RH, Bourton JL, Burns DA, Breathnach SM, editors. Textbook of Dermatology, 6th ed. London: Blackwell Publishing Ltd. 1998; p. 1215-53.
Levis WR, Ernst JD. Mycobacterium leprae (leprosy, Hansen’s disease). In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases. 6th ed. New York: Elsevier/Churchill Livingstone; 2005. p. 2886-96.
Martins AC, Castro Jde C, Moreira JS. A ten-year historic study of paranasal cavity endoscopy in patients with Leprosy. Braz J Otorhinolaryngol 2005;71(5):609-15.
World Health Organization (WHO). Leprosy [Online]. Revised October 2005. Available from:http://www.who.int/lep/en/
Bhat R, Sharma VK, Deka RC. Otorhinolaryngologic manifestations of leprosy. Int J Dermatol 2007;46(6):600-6.
Beyene D, Aseffa A, Harboe M, Kidane D, Macdonald M, Klatser PR, et al. Nasal carriage of Mycobacterium leprae DNA in healthy individuals in Lega Robi village, Ethiopia. Epidemiol Infect 2003;131(2):841-8.
Job A, Chacko CJ. Reactional states in the nasal mucosa: a clinical and histopathological study. Int J Lepr Other Mycobact Dis 1988;56(4):523-6.
Soni NK, Epistaxis and Leprosy. Indian J Lepr 1988;60(4):562-5.
Soni NK, Chatterji P. Hansen's disease and olfaction. Int J Lepr Other Mycobact Dis 1984;52(3):339-42.
Soni NK. Gustatory rhinorrhoea syndrome: result of misreinnervation in leprosy. Indian J Lepr 1988;60(3):418-21.
Yasushi S, Takahashi T, Ishii H. A care of Leprosyfollowed by nasal bleeding. Jpn J Clin Dermatol 2002;56(13):1048-51.
Kim YR, Chung YS, Jang YJ, Lee BJ. A Case of Nasal Lepromatous Leprosy. Korean J Otolaryngol Head Neck Surg 2005;48(4):547-50.
Ishii N. Recent advances in the treatment of leprosy. Dermatol Online J 2003;9(2):5.
| Files | ||
| Issue | Vol 47, No 6 (2009) | |
| Section | Original Article(s) | |
| Keywords | ||
| Leprosy bacillus nose | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
