Huge Myxoid Liposarcoma of the Esophagus: A Case Report
Although esophageal liposarcoma is an extremely rare tumor, liposarcoma is the most common soft tissue sarcoma in adults. Liposarcoma is currently classified into the types of well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated liposarcoma. Up to now only a few cases of esophagus liposarcoma have been described in the world literature. We describe a myxoid type liposarcoma of the esophagus in a 68 year old man presented with hoarseness and intermittent dysphagea to solid food. He had a huge mass in his mouth which was mobile with gag reflex. A barium swallow, esophageal manometery and CT scan of the esophagus have not clearly revealed the mass. After endoscopic surgical resection of the tumor the histological examination revealed a myxoid liposarcoma. Both the presenting signs and symptoms and the histology type are rare for such tumor. This case demonstrate a rare differential diagnosis of intermittent dysphagia as early diagnosis is so important in those tumors and should kept in mind them, although they are quite rare.
Allen PW. Tumors and Proliferations of Adipose Tissue: Clinicopathologic Approach. New York: Masson Publishing; 1981.
Hajdu S. Pathology of Soft Tissue Tumors. Philadelphia, PA: Lea and Febiger; 1979.
Cody HS 3rd, Turnbull AD, Fortner JG, Hajdu SI. The continuing challenge of retroperitoneal sarcomas. Cancer 1981;47(9):2147-52.
Saunders JR, Jaques DA, Casterline PF, Percarpio B, Goodloe S Jr. Liposarcomas of the head and neck: a review of the literature and addition of four cases. Cancer 1979;43(1):162-8.
Enzinger FM, Weiss SW. Liposarcoma. In: Enzinger FM, Weiss SW, editors. Soft Tissue Tumors. 3rd ed. St Louis: Mosby; 1995. p. 431-66.
Enterline HT, Culberson JD, Rochlin DB, Brady LW. Liposarcoma: A clinical and pathological study of 53 cases. Cancer 1960;13:932-50.
Evans HL. Liposarcoma: a study of 55 cases with a reassessment of its classification. Am J Surg Pathol 1979;3(6):507-23.
Garcia M, Buitrago E, Bejarano PA, Casillas J. Large esophageal liposarcoma: a case report and review of the literature. Arch Pathol Lab Med 2004;128(8):922-5.
Mansour KA, Fritz RC, Jacobs DM, Vellios F. Pedunculated liposarcoma of the esophagus: a first case report. J Thorac Cardiovasc Surg 1983;86(3):447-50.
Bréhant O, Pessaux P, Hennekinne-Mucci S, Barrière E, D'Aubigny N, Aubé C, Boyer J, Arnaud JP. Giant pedunculated liposarcoma of the esophagus. J Am Coll Surg 2004;198(2):320-1.
Boggi U, Viacava P, Naccarato AG, Giulianotti PC, di Candio G, Battolla L, Mosca F. Giant pedunculated liposarcomas of the esophagus: literature review and case report. Hepatogastroenterology 1997;44(14):398-407.
Chung JJ, Kim MJ, Kim JH, Lee JT, Yoo HS, Kim KW. Imaging findings of giant liposarcoma of the esophagus. Yonsei Med J 2003;44(4):715-8.
Razzuk MA, Urschel HC Jr, Race GJ, Nathan MJ, Paulson DL. Pseudosarcoma of the esophagus. A case report. J Thorac Cardiovasc Surg 1971;61(4):650-3.
Fearon B. Lower esophageal disease in infants and children. Ann Otol Rhinol Laryngol 1961;70:1124-39.
Temes R, Quinn P, Davis M, Endara S, Follis F, Pett S, Wernly J. Endoscopic resection of esophageal liposarcoma. J Thorac Cardiovasc Surg 1998;116(2):365-7.
Hirose S, Funaki H, Isomoto T, Iizuka T. A case of cancer of the esophagus accompanied by postoperative fulminant hepatitis. Rinsho Kyobu Geka 1989;9(1):85-8.
Arteaga-González I, Fernandez EL, Higa K. A minimal invasive approach of esophageal liposarcoma. J Laparoendosc Adv Surg Tech A 2008;18(2):266-70.
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