Concurrent Oncocytoma and Two Angiomyolipomas in a Diabetic Kidney: A Very Rare Condition

  • Fariba Abbasi Department of Pathology, Solid Tumor Research Center, Urmia University of Medical Sciences, Urmia, Iran.
  • Ata Abbasi Mail Department of Pathology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
  • Mansour Alizadeh Department of Urology, Urmia Urology and Nephrology Research Center, Urmia University of Medical Sciences, Urmia, Iran.
  • Parisa Modarresi Department of Pathology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Keywords:
Angiomyolipoma, Oncocytoma, Diabetic nephropathy, Simultaneous occurrence

Abstract

Angiomyolipoma (AML) and oncocytoma are uncommon benign neoplasms of the kidney which their simultaneous occurrence in the same kidney is extremely rare. This study reports a 60-year-old diabetic woman with the rare simultaneous occurrence of three renal masses. Histologic evaluation revealed two angiomyolipomas and one oncocytoma within the same kidney, in a background of histologic features of diabetic nephropathy. Renal angiomyolipoma and oncocytoma are uncommon neoplasms, and their simultaneous occurrence in the same kidney is extremely rare.

References

Teodosiosis S, Yiallourou A, Kyriazi M, Anastasopoulos G, Kairi-Vassilatou E, Dafnios N, Vassiliou I. Unilateralsimultaneous renal oncocytoma and angiomyolipoma:case report. Cases J 2009;2:9093.

Al-Thani H, El-Menyar A, Al-Sulaiti M, El-Mabrok J,Hajaji K, Elgohary H, et al. Clinical Presentation,Management, and Outcome of Patients with IncidentalRenal Angiomyolipoma in Qatar Oman Med 2014;29:419-24.

Perez-Ordonez, B, Hamed G, Campbell S, Erlandson RA,Russo P, Gaudin PB, et al. Renal Oncocytoma: AClinicopathologic Study of 70 Cases. Am J surg pathol1997;21:871-83.

Fairchild TN, Dail DH, Brannen GE. Renal oncocytoma.Bilateral, multifocal. Urology 1983;22:355-59.

Tamboli P, Ro JY, Amin MB, Ligato S, Ayala AG.Benign tumors and tumor-like lesions of the adult kidney.Part II: Benign mesenchymal and mixed neoplasms, andtumor-like lesions. Adv Anat Pathol 2000;7:47-66.

Ashfaq R, Weinberg AG, Albores-Saavedra J. enalangiomyolipomas and HMB-45 reactivity. Cancer1993;71:3091-97.

Pillay K, Lazarus J, Wainwright HC. Association ofangiomyolipoma and oncocytoma of the kidney: a casereport and review of the literature. J Clin Pathol2003;56:544-47

Davis Jr CJ, Sesterhenn IA, Mostofi FK. Renaloncocytoma: clinicopathological study of 166 patients. JUrogenit Pathol 1991;1:41-52.

Amin MB, Tickoo SK, Crotty TB, Farrow GM.Concurrent renal oncocytoma and renal cell carcinomawithin the same kidney: diagnostic implications. Am JSurg Pathol 1998;22:510.

Bahrami A, Schwartz NR, Ayala AG, Goldfarb RA,Brady JR, Takei H, et al. Concurrent angiomyolipomaand two oncocytomas in the same kidney. Ann DiagnPathol 2007;11:132-36.

Jimenez RE, Eble JN, Reuter VE, Epstein JI, Folpe AL,de Peralta-Venturina M, et al. Concurrentangiomyolipoma and renal cell neoplasia: a study of 36cases. Mod Pathol 2001;14:157-63.

Delgado R, de Leon Bojorge B, Albores-Saavedra J.Atypical angiomyolipoma of the kidney: a distinctmorphologic variant that is easily confused with a varietyof malignant neoplasms. Cancer 1998;83:1581–92.

Martignoni G, Pea M, Bonetti F, Brunelli M, Eble JN.Oncocytoma-like angiomyolipoma: a clinicopathologicand immunohistochemical study of 2 cases. Arch PatholLab Med 2002;126:610-2.

Published
2017-09-16
How to Cite
1.
Abbasi F, Abbasi A, Alizadeh M, Modarresi P. Concurrent Oncocytoma and Two Angiomyolipomas in a Diabetic Kidney: A Very Rare Condition. Acta Med Iran. 55(7):470-473.
Section
Case Report(s)