Treatment of an Early Kaposi’s Sarcoma Case Post Kidney Transplantation by Sirolimus: A Case Report
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Abstract
Kaposi᾽s sarcoma (KS) can develop in 0.06% to 4.1% of kidney transplant recipients. Here we describe a case of 50-year-old man who developed KS a few months after kidney transplantation. After transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (ATG) for five days. At the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, tTacrolimus (Pprograf®) 4 mg/day, and mycophenolate mofetil (MMF) 2 gr/day, while he also took Vvalcyte and diltiazem. Once diagnosed with KS, the Prograf® (tacrolimus) was replaced by prednisolone (5 mg/day) and sirolimus (2 mg/day). Gradually the skin nodule on the patient arm disappeared, and the others nodule on the right his leg was decreased. It seems that the examination of skin should be a part of regular follow-up and dermatologist examination is recommended every 6 months.
Raeisi D, Payandeh M, Madani SH, Zare ME, Kansestani AN, et al. Kaposi's Sarcoma after Kidney Transplantation: a 21-Years Experience. Int J Hematol Oncol Stem Cell Res 2013;7:29-33.
El-Agroudy AE, El-Baz MA, Ismail AM, Ali-El-Dein B, El-Dein AB, Ghoneim MA. Clinical features and course of Kaposi's sarcoma in Egyptian kidney transplant recipients. Am J Transplant 2003;3:1595-9.
Yildirim Y, Ozyilkan O, Emiroglu R, Demirhan B, Karakayali H, Haberal M. Early diagnosis of cancer in renal transplant patients: a single center experience. Asian Pac J Cancer Prev 2006;7:336-9.
Einollahi B. Unusual site of kaposi sarcoma after kidney transplantation. Iran J Kidney Dis 2012;6:164-5.
Cattani P, Capuano M, Graffeo R, Ricci R, Cerimele F, Cerimele D, et al. Kaposi's sarcoma associated with previous human herpesvirus 8 infection in kidney transplant recipients. J Clin Microbiol 2001;39:506-8.
Lahlaoui H, Niija H, Ben Moussa M. Seroprevalence of human herpesvirus 8 in kidney transplant recipients in a single-center study from Tunisia. Iran J Kidney Dis 2012;6:14-6.
De Blasio A, Palmiero G, Russo D. Kaposi's sarcoma occurring in a young black man after kidney transplantation. Nephrol Dial Transplant 2005;20:2839-41.
Moosa MR. Kaposi's sarcoma in kidney transplant recipients: a 23-year experience. QJM 2005;98:205-14.
Dow DE, Cunningham CK, Buchanan AM. A Review of Human Herpesvirus 8, the Kaposi's Sarcoma-Associated Herpesvirus, in the Pediatric Population. J Pediatric Infect Dis Soc 2014;3:66-76.
Euvrard S, Kanitakis J, Claud A. Skin Cancers after Organ Transplantation Medical Progress: N Engl J Med 2003;348:1681-91.
| Files | ||
| Issue | Vol 55, No 2 (2017) | |
| Section | Case Report(s) | |
| Keywords | ||
| Kaposi’s sarcoma End stage renal disease Kidney Transplantation | ||
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