Case Report

Unusual Presentation of Schwannoma: A Case Report and Literature Review

Abstract

Schwannoma is a benign encapsulated tumor of the nerve sheath. Amongst other sites, it develops in the posterior mediastinum in the costovertebral sulcus. We herein present a case of a 68-year-old woman with an incidental finding of a subcarinal mass. Radiological and histopathological studies were suggestive of schwannoma. Therefore, the mass was completely resected through a right thoracotomy, and a definite histopathological diagnosis was established. Although the subcarinal area is a rare site for this tumor to appear, the schwannoma should be considered as part of the differential diagnosis of lesions in the subcarinal region. Treatment of choice is the nerve-sparing surgical excision of the mass with excellent prognosis. A review of the literature on this topic was performed.

References:

Ciftci F, Kaya AG, Karacay E, Ciledag A, Ceyhan K, Kaya A,et al.,Mediastinal Schwannoma with Atypical Localization Diagnosed by Endobronchial Ultrasound. Clin Respir J. 2015 Nov 24.

Rammos KS, Rammos SK, Foroulis CN, Zaramboukas TK Schwannoma of the vagus nerve, a rare middle mediastinal neurogenic tumor: case report. J Cardiothorac Surg. 2009 Nov 26;4:68.

Das A, Choudhury S, Basuthakur S, Mukhopadhyay A, Mukherjee S. Massive hemoptysis: a rare presentation of posterior mediastinal, giant, benign vagal schwannoma. Arch Iran Med. 2014 Nov;17(11):779-82.

Negri G, Bandiera A, Carretta A, Puglisi A, Mandelli C, Ciriaco P et al., Unusual Presentation of Mediastinal Neurogenic Tumours. Case Rep Surg. 2013; 2013: 414260.

Strollo DC, Rosado-de-Christenson ML, Jett JR. Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 1997 Nov 5;112(5):1344-57.

Knight DM, Birch R, Pringle J. Benign solitary schwannomas: a review of 234 cases. J Bone Joint Surg Br. 2007 Mar;89(3):382-7.

Ishibashi H, Ohta S, Hirose M, Togo T, Muro H, Nakajima N. Middle mediastinal schwannoma originating from the intrathoracic vagal nerve with difficulty in swallowing; report of a case. Kyobu Geka. 2012 Aug;65(9):840-3.

Dahdah J, Validire P, Grigoroiu M, Lenoir S, Gossot D, Stern JB. Cystic mediastinal schwannoma appended to the vagus nerve. Rev Mal Respir. 2016 May;33(5):383-7.

Endo S, Murayama F, Yamaguchi T, Haseqawa T, SoharaY, Fuse K, et al.,Subcarinal neurogenic tumor: report of a case. Surg Today. 1998;28(12):1307-9.

Odaka M, Shibasaki T, Asano H, Marushima H, Yamashita M, Morikawa T. A surgical case of subcarinal schwannoma. The Journal of the Japanese Association for Chest Surgery Vol. 30 (2016) No. 2 p. 164-168

Singhal M, Misra V, Dhingra V, Misra SP. Giant cellular neurilemmoma, a rare mesenchymal tumor of the oesophagus: A case report with review of literature. International Journal of Case Reports and Images 2012;3(10):35–38.

Files
IssueVol 56, No 10 (2018) QRcode
SectionCase Report(s)
Keywords
Neurogenic tumor Schwannoma Mediastinal tumor

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Kakos C, Mitsos S, Madouros N, Patrini D, Khiroya R, Borg E, Lawrence D, Panagiotopoulos N. Unusual Presentation of Schwannoma: A Case Report and Literature Review. Acta Med Iran. 2019;56(10):681-683.