Esophageal Atresia: Recent Five Years’ Mortality and Morbidity
-
Mehrdad Goodarzi
,
Hossein Ali Khazaei
,
Bahar Ashjaei
,
Maryam Ghavami
,
Mansour Mollaeian
,
Nora Bigdeli
,
Ali Talebi
,
Azita Parvizizadeh
,
Gholamreza Badfar
,
Alireza Ebrahim Soltani
,
Alireza Nahvi
,
Valiullah Mehrabi
,
Hedayatollah Nahvi
Abstract
Esophageal atresia (EA) is a rare congenital anomaly that may be isolated or associated with other anomalies requiring prompt medical and surgical planning for optimal result. This study was conducted to show our recent experience on the outcome of treated patients in two hospitals affiliated to Tehran University of Medical Sciences (TUMS). From January 2008 to May 2013 records of 43 neonates patients (23 male) with EA admitted in 2 children centers and all related data including demographic, diagnostic associated anomalies, surgical approaches, birth weight, mortality, and complications were collected. Inability of feeding and swallowing was the most common symptoms (in 90,6%), associated CHD (44%), and Type C (EA) was the most common type of EA observed in 86% patients, The mortality rate was 4.7% and most common complication was anastomotic stricture (AS) in 60% of patients. Our study showed that despite improvements in management and survival of an infant with (EA), still sepsis, aspiration pneumonia, prematurity, and low birth weight and severe Congenital Heart Disease (CHD) were independent etiology of death and birth weight < 2.500 gr has a significant effect on the occurrence of postoperative complications.
Pedersen RN, Calzolari E, Husby S, Garne E. OEA: prevalence, prenatal diagnosis and associated anomalies in 23 European regions. Arch Dis Child. 2012 Mar;97(3):227-32.
Wang B, Tashiro J, Allan BJ, Sola JE, Parikh PP, Hogan AR, et al. A nationwide analysis of clinical outcomes among newborns with EA and tracheoesophageal fistulas in the United States. J Surg Res. 2014 Aug;190(2):604-12.
Langer JC, Hussain H, Khan A, Minkes RK, Gray D, Siegel M, et al. Prenatal diagnosis of EA using sonography and magnetic resonance imaging. J Pediatr Surg. 2001 May;36(5):804-7.
Stringer MD, McKenna KM, Goldstein RB, Filly RA, Adzick NS, Harrison MR. Prenatal diagnosis of EA. J Pediatr Surg. 1995 Sep;30(9):1258-63.
Orford J, Cass DT, Glasson MJ. Advances in the treatment of oEA over three decades: the 1970s and the 1990s. Pediatr Surg Int. 2004 Jun;20(6):402-7.
Goyal A, Jones MO, Couriel JM, Losty PD. OEA and tracheo-oesophageal fistula. Arch Dis Child Fetal Neonatal Ed. 2006 Sep;91(5):F381-4.
Harmon CM CACaote, editor. Congenital anomalies of the esophagus.2006.
Demircan M, Aksoy T, Ceran C, Kafkasli A. Tracheal agenesis and EA with proximal and distal bronchoesophageal fistulas. J Pediatr Surg. 2008 Aug;43(8):e1-3.
Felix JF, Tibboel D, de Klein A. Chromosomal anomalies in the aetiology of oEA and tracheo-oesophageal fistula. Eur J Med Genet. 2007 May-Jun;50(3):163-75.
Stark Z, Patel N, Clarnette T, Moody A. Triad of tracheoesophageal fistula-EA, pulmonary hypoplasia, and duodenal atresia. J Pediatr Surg. 2007 Jun;42(6):1146-8.
Deurloo JA, Ekkelkamp S, Schoorl M, Heij HA, Aronson DC. EA: historical evolution of management and results in 371 patients. Ann Thorac Surg. 2002 Jan;73(1):267-72.
Poenaru D, Laberge JM, Neilson IR, Nguyen LT, Guttman FM. A more than 25-year experience with end-to-end versus end-to-side repair for EA. J Pediatr Surg. 1991 Apr;26(4):472-6; discussion 6-7.
Koivusalo AI, Pakarinen MP, Rintala RJ. Modern outcomes of oEA: single centre experience over the last twenty years. J Pediatr Surg. 2013 Feb;48(2):297-303.
Baird R, Laberge JM, Levesque D. Anastomotic stricture after EA repair: a critical review of recent literature. Eur J Pediatr Surg. 2013 Jun;23(3):204-13.
Montgomery M, Frenckner B. EA: mortality and complications related to gastroesophageal reflux. Eur J Pediatr Surg. 1993 Dec;3(6):335-8.
Taylor AC, Breen KJ, Auldist A, Catto-Smith A, Clarnette T, Crameri J, et al. Gastroesophageal reflux and related pathology in adults who were born with EA: a long-term follow-up study. Clin Gastroenterol Hepatol. 2007 Jun;5(6):702-6.
Orenstein SR, Izadnia F, Khan S. Gastroesophageal reflux disease in children. Gastroenterol Clin North Am. 1999 Dec;28(4):947-69.
Spitz L, Kiely E, Brereton RJ. EA: five year experience with 148 cases. J Pediatr Surg. 1987 Feb;22(2):103-8.
Tsai JY, Berkery L, Wesson DE, Redo SF, Spigland NA. EA and tracheoesophageal fistula: surgical experience over two decades. Ann Thorac Surg. 1997 Sep;64(3):778-83; discussion 83-4.
Engum SA, Grosfeld JL, West KW, Rescorla FJ, Scherer LR, 3rd. Analysis of morbidity and mortality in 227 cases of EA and/or tracheoesophageal fistula over two decades. Arch Surg. 1995 May;130(5):502-8; discussion 8-9.
Provenzano MJ, Rutter MJ, von Allmen D, Manning PB, Paul Boesch R, Putnam PE, et al. Slide tracheoplasty for the treatment of tracheoesophogeal fistulas. J Pediatr Surg. 2014 Jun;49(6):910-4.
Spitz L. OEA. Orphanet J Rare Dis. 2007 May 11;2:24.
Waterston DJ, Carter RE, Aberdeen E. OEA: tracheo-oesophageal fistula. A study of survival in 218 infants. Lancet. 1962 Apr 21;1(7234):819-22.
Davari HA, Hosseinpour M, Nasiri GM, Kiani G. Mortality in EA: Assessment of probable risk factors (10 years' experience). J Res Med Sci. 2012 Jun;17(6):540-2.
| Files | ||
| Issue | Vol 56, No 10 (2018) | |
| Section | Articles | |
| Keywords | ||
| Outcome Birth-weight Congenital heart disease Operation EA | ||
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