Acalculous Cholecystitis, Acute Hepatitis and Hemolytic Anemia Associated With Epstein-Barr Virus: A Case Report
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Abstract
Epstein-Barr virus (EBV) is a member of the herpes virus family and is characterized by fever, lymphadenopathy, and sore throat. In this report, we present a 20-year-old woman with a four-day history of fever, chills, nausea, vomiting, jaundice and abdominal pain, and a diagnosis of acalculous cholecystitis, acute hepatitis with hemolytic anemia due to infectious mononucleosis. After the confirmation of acute acalculous cholecystitis along with hemolytic anemia, prednisolone was initiated for the patient. Supportive measures resolved the symptoms of acalculous cholecystitis.
1. Macsween KF, Crawford DH. Epstein-Barr virus-recent advances. Lancet Infect Dis 2003;3:131-40.
2. E. Lagona, F. Sharifi, A. Voutsioti, A. Mavri, M. Markouri, and A. Attilakos, “Epstein-barr virus infectious mononucleosis associated with acute acalculous cholecystitis,” Infection, vol. 35, no. 2, pp. 118–119, 2007.
3. Jimenez-Saenz M, Perez-Pozo JM, Leal-Luna A et al: Lethal liver failure in an elderly patient with hepatitis B superinfected with Epstein-Barr virus. Eur Gastroenterol Hepatol, 2002; 14: 1283–84.
4. Barie PS, Eachempati SR. Acute acalculous cholecystitis. Gastroenterol Clin North Am 2010;39:343-57.
5. D. Koch, H. C. M. Van Den Bosch, and B. Bravenboer, “Epstein-Barr virus-associated cholecystitis,” Annals of Internal Medicine, vol. 146, no. 11, pp. 826–827, 2007.
6. Iaria, L. Arena, G. DiMaio et al., “Acute acalculous cholecystitis during the course of primary Epstein-Barr virus infection: a new case and a review of the literature,” International Journal of Infectious Diseases, vol. 12, no. 4, pp. 391–395, 2008.
7. Cholongitas, K. Katsogridakis, andM.Dasenaki, “Acalculous cholecystitis during the course of acute Epstein-Barr virus infection,” International Journal of Infectious Diseases, vol. 13, no. 3, pp. e129–e130, 2009.
8. Chalupa P, Kaspar M, Holub M. Acute acalculous cholecystitis with pericholecystitis in a patient with Epstein-Barr Virus infectious mononucleosis. Medical Science Monitor. 2009 Jan 29;15(2):CS30-3.
9. Hagel S, Bruns T, Kantowski M, Fix P, Seidel T, Stallmach A. Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein–Barr virus infection under azathioprine. Inflammatory bowel diseases. 2009 Jan 9;15(11):1613-6.
10. Beltrame, A. Andres, F. Tona, and C. Sperti, “Epstein-barr virus—associated acute acalculous cholecystitis in an adult,” American Journal of Case Reports, vol. 13, pp. 153–156, 2012.
11. Nagdev and J. Ward, “Bedside ultrasound diagnosis of acalculous cholecystitis from Epstein-Barr virus,” Western Journal of Emergency Medicine, vol. 12, no. 4, pp. 481–483, 2011.
12. Dylewski, “Acute acalculous cholecystitis caused by Epstein-Barr virus infection,” Clinical Microbiology Newsletter, vol. 34, no. 1, pp. 7–8, 2012.
13. F. Carrascosa, J.-R. S. Caviedes, G. Soler-Dorda, and C. Saiz-P´erez, “Epstein-Barr virus acute cholecystitis,” BMJ Case Reports, vol. 2012, 2012.
14. A.Gagneux-Brunon, F. Suy, A. Pouvaret et al., “Acute acalculous cholecystitis, a rare complication of Epstein-Barr virus primary infection: report of two cases and review,” Journal of Clinical Virology, vol. 61, no. 1, pp. 173–175, 2014.
15. F. Celik, F. Tekin, T. Yamazhan, and F. Gunsar, “Epsteinbarr vir¨us associated acute acalculous cholecystitis,” Journal of Gastroenterology andHepatology Research, vol. 3, no. 7,pp. 1179– 1180, 2014.
16. J. Agergaard and C. S. Larsen, “Acute acalculous cholecystitis in a patient with primary Epstein-Barr virus infection: a case report and literature review,” International Journal of Infectious Diseases, vol. 35, pp. 67–72, 2015.
17. T. Koufakis and I. Gabranis, “Another report of acalculous cholecystitis in a greek patient with infectious mononucleosis: a matter of luck or genetic predisposition?” Case Reports in Hepatology, vol. 2016, Article ID 6080832, 3 pages, 2016.
18. Sheybani F, Naderi H, Erfani SS, Gharib M. A complicated course of acute viral induced pharyngitis, icteric hepatitis, acalculous cholecystitis, and skin rash. Case reports in medicine. 2016;2016.
19. Yesilbag Z, Karadeniz A, Kaya FO. Acute acalculous cholecystitis: a rare presentation of primary Epstein-Barr virus infection in adults—case report and review of the literature. Case reports in infectious diseases. 2017;2017.
20. Prassouli A, Panagiotou J, Vakaki M, et al. Acute acalculous cholecystitis as the initial presentation of primary Epstein-Barr virus infection. J Pediatr Surg 2007;42:E11-3.
21. Barie PS, Eachempati SR. Acute acalculous cholecystitis. Gastroenterology Clinics. 2010 Jun 1;39(2):343-57.
22. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ. A method for estimating the probability of adverse drug reactions. Clinical Pharmacology & Therapeutics. 1981 Aug 1;30(2):239-45.
2. E. Lagona, F. Sharifi, A. Voutsioti, A. Mavri, M. Markouri, and A. Attilakos, “Epstein-barr virus infectious mononucleosis associated with acute acalculous cholecystitis,” Infection, vol. 35, no. 2, pp. 118–119, 2007.
3. Jimenez-Saenz M, Perez-Pozo JM, Leal-Luna A et al: Lethal liver failure in an elderly patient with hepatitis B superinfected with Epstein-Barr virus. Eur Gastroenterol Hepatol, 2002; 14: 1283–84.
4. Barie PS, Eachempati SR. Acute acalculous cholecystitis. Gastroenterol Clin North Am 2010;39:343-57.
5. D. Koch, H. C. M. Van Den Bosch, and B. Bravenboer, “Epstein-Barr virus-associated cholecystitis,” Annals of Internal Medicine, vol. 146, no. 11, pp. 826–827, 2007.
6. Iaria, L. Arena, G. DiMaio et al., “Acute acalculous cholecystitis during the course of primary Epstein-Barr virus infection: a new case and a review of the literature,” International Journal of Infectious Diseases, vol. 12, no. 4, pp. 391–395, 2008.
7. Cholongitas, K. Katsogridakis, andM.Dasenaki, “Acalculous cholecystitis during the course of acute Epstein-Barr virus infection,” International Journal of Infectious Diseases, vol. 13, no. 3, pp. e129–e130, 2009.
8. Chalupa P, Kaspar M, Holub M. Acute acalculous cholecystitis with pericholecystitis in a patient with Epstein-Barr Virus infectious mononucleosis. Medical Science Monitor. 2009 Jan 29;15(2):CS30-3.
9. Hagel S, Bruns T, Kantowski M, Fix P, Seidel T, Stallmach A. Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein–Barr virus infection under azathioprine. Inflammatory bowel diseases. 2009 Jan 9;15(11):1613-6.
10. Beltrame, A. Andres, F. Tona, and C. Sperti, “Epstein-barr virus—associated acute acalculous cholecystitis in an adult,” American Journal of Case Reports, vol. 13, pp. 153–156, 2012.
11. Nagdev and J. Ward, “Bedside ultrasound diagnosis of acalculous cholecystitis from Epstein-Barr virus,” Western Journal of Emergency Medicine, vol. 12, no. 4, pp. 481–483, 2011.
12. Dylewski, “Acute acalculous cholecystitis caused by Epstein-Barr virus infection,” Clinical Microbiology Newsletter, vol. 34, no. 1, pp. 7–8, 2012.
13. F. Carrascosa, J.-R. S. Caviedes, G. Soler-Dorda, and C. Saiz-P´erez, “Epstein-Barr virus acute cholecystitis,” BMJ Case Reports, vol. 2012, 2012.
14. A.Gagneux-Brunon, F. Suy, A. Pouvaret et al., “Acute acalculous cholecystitis, a rare complication of Epstein-Barr virus primary infection: report of two cases and review,” Journal of Clinical Virology, vol. 61, no. 1, pp. 173–175, 2014.
15. F. Celik, F. Tekin, T. Yamazhan, and F. Gunsar, “Epsteinbarr vir¨us associated acute acalculous cholecystitis,” Journal of Gastroenterology andHepatology Research, vol. 3, no. 7,pp. 1179– 1180, 2014.
16. J. Agergaard and C. S. Larsen, “Acute acalculous cholecystitis in a patient with primary Epstein-Barr virus infection: a case report and literature review,” International Journal of Infectious Diseases, vol. 35, pp. 67–72, 2015.
17. T. Koufakis and I. Gabranis, “Another report of acalculous cholecystitis in a greek patient with infectious mononucleosis: a matter of luck or genetic predisposition?” Case Reports in Hepatology, vol. 2016, Article ID 6080832, 3 pages, 2016.
18. Sheybani F, Naderi H, Erfani SS, Gharib M. A complicated course of acute viral induced pharyngitis, icteric hepatitis, acalculous cholecystitis, and skin rash. Case reports in medicine. 2016;2016.
19. Yesilbag Z, Karadeniz A, Kaya FO. Acute acalculous cholecystitis: a rare presentation of primary Epstein-Barr virus infection in adults—case report and review of the literature. Case reports in infectious diseases. 2017;2017.
20. Prassouli A, Panagiotou J, Vakaki M, et al. Acute acalculous cholecystitis as the initial presentation of primary Epstein-Barr virus infection. J Pediatr Surg 2007;42:E11-3.
21. Barie PS, Eachempati SR. Acute acalculous cholecystitis. Gastroenterology Clinics. 2010 Jun 1;39(2):343-57.
22. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ. A method for estimating the probability of adverse drug reactions. Clinical Pharmacology & Therapeutics. 1981 Aug 1;30(2):239-45.
| Files | ||
| Issue | Vol 58, No 3 (2020) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/acta.v58i3.3776 | |
| Keywords | ||
| Epstein-barr virus Infectious mononucleosis Acalculous cholecystitis Hemolytic anemia Hepatitis | ||
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How to Cite
1.
Hakamifard A, Soltani R, Hjigholami A, Yaghoubi S. Acalculous Cholecystitis, Acute Hepatitis and Hemolytic Anemia Associated With Epstein-Barr Virus: A Case Report. Acta Med Iran. 2020;58(3):130-133.
