Original Article

Evaluation of Impact of Life-Style-Related Risk Factors in Age-Related Cataract

Life-style and age-related cataract

Abstract

Cataract is a multifactorial ocular disease, resulting in turbidity or opacity of the lens of the eyes, which leads to blindness or reduction of visuality. The different environmental, socio-economical, and lifestyle factors indicate as risk factors of age-related cataracts. The aim of this study was the evaluation of daily activity, dietary regimen, residence location and etc., as risk factors of age-related cataracts. In this census, a cross-sectional study was performed on 353 patients with age-related cataract underwent surgery, who referred to Rouhani Hospital in Babol, Iran from 2018 to 2019, and 343 healthy individuals. The lifestyle-related information was collected from all individuals via the designed questionnaire. Our results showed that there were significant correlations between the birth/residence in the village (comparing to city, P<0.001), abnormal sleeping time (P<0.001), daily activity (and being outdoor, P<0.001), and use of solid oil (P<0.001) with increasing in age-related cataracts. Furthermore, the use of antioxidant-containing fruits significantly reduces the risk of age-related cataracts. Our results established that lifestyle clearly has a golden impact on age-related cataracts. The reduction in daily activity, normal sleeping time, and more use of antioxidant-containing dietary regimen play a preventive role in age-related cataracts.

1. Zhang XH, Da Wang J, Jia HY, Zhang JS, Li Y, Xiong Y, et al. Mutation profiles of congenital cataract genes in 21 northern Chinese families. Mol Vis 2018;24:471-7.
2. Agarwal A, Kumar DA. Cost-effectiveness of cataract surgery. Curr Opin Ophthalmol 2011;22:15-8.
3. Taylor A. Associations between nutrition and cataract. Nutr Rev 1989;47:225-34.
4. Peterson SR, Silva PA, Murtha TJ, Sun JK. Cataract Surgery in Patients with Diabetes: Management Strategies. Semin Ophthalmol 2018;33:75-82.
5. Pichi F, Lembo A, Serafino M, Nucci P. Genetics of Congenital Cataract. Dev Ophthalmol 2016;57:1-14.
6. Park S, Choi NK. Serum 25-hydroxyvitamin D and Age-Related Cataract. Ophthalmic Epidemiol 2017;24:281-6.
7. Rasoulinejad SA, Zarghami A, Hosseini SR, Rajaee N, Rasoulinejad SE, Mikaniki E. Prevalence of age-related macular degeneration among the elderly. Caspian J Intern Med 2015;6:141-7.
8. Asbell PA, Dualan I, Mindel J, Brocks D, Ahmad M, Epstein S. Age-related cataract. Lancet 2005;365:599-609.
9. Goodarzi M, Zal F, Malakooti M, Sadeghian M, S S. Inhibitory activity of flavonoids on the lens aldose reductase of healthy and diabetic rats. Acta Med Iran 2006;44:41-5.
10. Li X, Cao X, Hou X, Bao Y. The Correlation of Age and Postoperative Visual Acuity for Age-Related Cataract. Biomed Res Int 2016;2016:7147543.
11. Hedayati H, Ghaderpanah M, Rasoulinejad SA, Montazeri M. Clinical Presentation and Antibiotic Susceptibility of Contact Lens Associated Microbial Keratitis. J Pathog 2015;2015:152767.
12. Schmitt C, Hockwin O. The mechanisms of cataract formation. J Inherit Metab Dis 1990;13:501-8.
13. Ahmadpour-Kacho M, Motlagh AJ, Rasoulinejad SA, Jahangir T, Bijani A, Pasha YZ. Correlation between hyperglycemia and retinopathy of prematurity. Pediatr Int 2014;56:726-30.
14. Rasoulinejad SA, Iri HO. Determination of serum lipid profile in patients with diabetic macular edema that referred to Shahid Beheshti and Ayatollah Rouhani Hospitals, Babol during 2011-2012. Caspian J Intern Med 2015;6:77-81.
15. Roberts JE. Ultraviolet radiation as a risk factor for cataract and macular degeneration. Eye Contact Lens 2011;37:246-9.
16. Tang Y, Wang X, Wang J, Jin L, Huang W, Luo Y, et al. Risk factors of age-related cataract in a Chinese adult population: the Taizhou Eye Study. Clin Exp Ophthalmol 2018;46:371-9.
17. Weikel KA, Garber C, Baburins A, Taylor A. Nutritional modulation of cataract. Nutr Rev 2014;72:30-47.
18. Cui YH, Jing CX, Pan HW. Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies. Am J Clin Nutr 2013;98:778-86.
19. Ghanavati M, Behrooz M, Rashidkhani B, Ashtray-Larky D, Zameni SD, Alipour M. Healthy Eating Index in Patients With Cataract: A Case-Control Study. Iran Red Crescent Med J 2015;17:e22490.
Files
IssueVol 59, No 2 (2021) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/acta.v59i2.5575
Keywords
Age-related cataract Life-style Risk factor Dietary regimen
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Roustaei G, Shomali F, Gholinia H, Farzin M, Rasoulinejad SA. Evaluation of Impact of Life-Style-Related Risk Factors in Age-Related Cataract. Acta Med Iran. 2021;59(2):91-96.