Acute Necrotizing Encephalopathy of Childhood (ANEC): A Case Report
-
Morteza Abouzaripour
,
Fardin Fathi
,
Bakhtyar Khosravi
,
Ehsan Motavasel
,
Ramiar Sharifi
,
Mohammad Bakhtiar Hesam Shariati
Abstract
Acute necrotizing encephalopathy (ANE) is an infrequent disease in childhood with Specific clinical complications. To date, the highest incidence of this disease has been reported in East Asian children. The clinical features of the disease include convulsions, frequent vomiting, and coma. Most of these patients die within days or cause severe neurological complications. The disease is characterized by symmetric and necrotic multifunctional lesions in the thalami and brainstem. We reported a 5-year-old girl infant from Besat Hospital, Sanandaj, Kurdistan, located in west of Iran.
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2. Mizuguchi M. Acute necrotizing encephalopathy of childhood: a novel form of acute encephalopathy prevalent in Japan and Taiwan. Brain Dev 1997;19:81-92.
3. Rad AH, Aminzadeh V. Acute Necrotizing Encephalopathy of Childhood (ANEC): A Case Report. Iran J Child Neurol 2017;11:75-7.
4. Barkovich AJ. Pediatric neuroimaging. Philadelphia: Lippincott Williams & Wilkins; 2005.
5. Ito Y, Ichiyama T, Kimura H, Shibata M, Ishiwada N, Kuroki H, et al. Detection of influenza virus RNA by reverse transcription‐PCR and proinflammatory cytokines in influenza‐virus‐associated encephalopathy. J Med Virol 1999;58:420-5.
6. Salehiomran MR, Nooreddini H, Baghdadi F. Acute necrotizing encephalopathy of childhood; a case report. Iran J Child Neurol 2013;7:51-4.
7. Wong A, Simon E, Zimmerman R, Wang HS, Toh CH, Ng SH. Acute necrotizing encephalopathy of childhood: correlation of MR findings and clinical outcome. AJNR Am J Neuroradiol 2006;27:1919-23.
8. Yagishita A, Nakano I, Ushioda T, Otsuki N, Hasegawa A. Acute encephalopathy with bilateral thalamotegmental involvement in infants and children: imaging and pathology findings. AJNR Am J Neuroradiol 1995;16:439-47.
9. Ong SCL, Nur Azidawati AH, Liew YH, Anita S. Acute necrotising encephalopathy of childhood: A review of two cases. Med J Malaysia 2017;72:311.
10. Ravid S, Topper L, Eviatar L. Acute necrotizing encephalopathy presenting as a basal ganglia syndrome. J Child Neurol 2001;16:461-2.
11. Kim JH, Kim IO, Lim MK, Park MS, Choi CG, Kim HW, et al. Acute necrotizing encephalopathy in Korean infants and children: imaging findings and diverse clinical outcome. Korean J Radiol 2004;5:171-7.
12. Malandrini A, Luchini D, Gambelli S, Gaudiano C, Berti G, Salvadori C, et al. A syndrome of bilateral hemorrhage of the thalamus and myocarditis with fatal course. J Clin Forensic Med 2004;11:208-10.
13. Seo HE, Hwang SK, Choe BH, Cho MH, Park SP, Kwon S. Clinical spectrum and prognostic factors of acute necrotizing encephalopathy in children. J Korean Med Sci2010;25:449-53.
14. Noble P. Denis Archibald Leigh. Psychiatr Bull 1998;22:648-9.
15. Porto L, Lanferman H, Möller-Hartmann W, Jacobi G, Zanella F. Acute necrotising encephalopathy of childhood after exanthema subitum outside Japan or Taiwan. Neuroradiology 1999;41:732-4.
16. İdiman E. Acute disseminated encephalomyelitis (ADEM). Turkiye Klinikleri J Int Medi Sci Infect Dis 2006;2:65.
17. Sazgar M, Robinson JL, Chan AK, Sinclair DB. Influenza B acute necrotizing encephalopathy: a case report and literature review. Pediatr Neurol 2003;28:396-9.
2. Mizuguchi M. Acute necrotizing encephalopathy of childhood: a novel form of acute encephalopathy prevalent in Japan and Taiwan. Brain Dev 1997;19:81-92.
3. Rad AH, Aminzadeh V. Acute Necrotizing Encephalopathy of Childhood (ANEC): A Case Report. Iran J Child Neurol 2017;11:75-7.
4. Barkovich AJ. Pediatric neuroimaging. Philadelphia: Lippincott Williams & Wilkins; 2005.
5. Ito Y, Ichiyama T, Kimura H, Shibata M, Ishiwada N, Kuroki H, et al. Detection of influenza virus RNA by reverse transcription‐PCR and proinflammatory cytokines in influenza‐virus‐associated encephalopathy. J Med Virol 1999;58:420-5.
6. Salehiomran MR, Nooreddini H, Baghdadi F. Acute necrotizing encephalopathy of childhood; a case report. Iran J Child Neurol 2013;7:51-4.
7. Wong A, Simon E, Zimmerman R, Wang HS, Toh CH, Ng SH. Acute necrotizing encephalopathy of childhood: correlation of MR findings and clinical outcome. AJNR Am J Neuroradiol 2006;27:1919-23.
8. Yagishita A, Nakano I, Ushioda T, Otsuki N, Hasegawa A. Acute encephalopathy with bilateral thalamotegmental involvement in infants and children: imaging and pathology findings. AJNR Am J Neuroradiol 1995;16:439-47.
9. Ong SCL, Nur Azidawati AH, Liew YH, Anita S. Acute necrotising encephalopathy of childhood: A review of two cases. Med J Malaysia 2017;72:311.
10. Ravid S, Topper L, Eviatar L. Acute necrotizing encephalopathy presenting as a basal ganglia syndrome. J Child Neurol 2001;16:461-2.
11. Kim JH, Kim IO, Lim MK, Park MS, Choi CG, Kim HW, et al. Acute necrotizing encephalopathy in Korean infants and children: imaging findings and diverse clinical outcome. Korean J Radiol 2004;5:171-7.
12. Malandrini A, Luchini D, Gambelli S, Gaudiano C, Berti G, Salvadori C, et al. A syndrome of bilateral hemorrhage of the thalamus and myocarditis with fatal course. J Clin Forensic Med 2004;11:208-10.
13. Seo HE, Hwang SK, Choe BH, Cho MH, Park SP, Kwon S. Clinical spectrum and prognostic factors of acute necrotizing encephalopathy in children. J Korean Med Sci2010;25:449-53.
14. Noble P. Denis Archibald Leigh. Psychiatr Bull 1998;22:648-9.
15. Porto L, Lanferman H, Möller-Hartmann W, Jacobi G, Zanella F. Acute necrotising encephalopathy of childhood after exanthema subitum outside Japan or Taiwan. Neuroradiology 1999;41:732-4.
16. İdiman E. Acute disseminated encephalomyelitis (ADEM). Turkiye Klinikleri J Int Medi Sci Infect Dis 2006;2:65.
17. Sazgar M, Robinson JL, Chan AK, Sinclair DB. Influenza B acute necrotizing encephalopathy: a case report and literature review. Pediatr Neurol 2003;28:396-9.
| Files | ||
| Issue | Vol 60 No 10 (2022) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/acta.v60i10.11560 | |
| Keywords | ||
| Complications Encephalopathy Thalamus Brain Neurological | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Abouzaripour M, Fathi F, Khosravi B, Motavasel E, Sharifi R, Hesam Shariati MB. Acute Necrotizing Encephalopathy of Childhood (ANEC): A Case Report. Acta Med Iran. 2022;60(10):655-658.
