2023 CiteScore: 0.7
pISSN: 0044-6025
eISSN: 1735-9694
Editor-in-Chief:
Ahmadreza Dehpour, PharmD, PhD
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE).
Vol XIII, No 3-4 (1970)
Articles
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Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.
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The effects of a prolonged oral administration of methylthiouracil was studied on the electrophoretically - separated serum protein fractions in 24 dogs. Though the statistical mean of changes in serum albumin and alpha2 globulin were highly significant but the individual alterations were not consistent and therefore on the basis of the available data there does not seem to be a characteristic electrophoretic pattern in the experimentally produced hypothyroidism in the dog. This finding is in agreement with the clinical electrophoretic pattern reported in the human spontaneous hypothyroidism.
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During a one year period of investigation in Teheran an average of 339 people in 93 families and from two different socio-economic levels wesre regulA significant increase in both streptococcal and non - streptococcal pharyngitis was seen during October and f"ovember. of 153 cases of phar yngitis seen, 53 (34,6%) patients were over 16 and 100 (65.2%) were under 16. 47 per cent of patients harbored beta hemolytic streptococcal, hence the infection rate per 100 persons per year for streptococcal sore throat was 2 1.2 per cent. No significant difference was seen with regard to pharyngitis among the two socio-economic groups. The overall carrier rate for beta hemolytic streptoc-occi during the year was 13.2;%. The ra te for the under 16 years was 16.0% and 9.2% for the over 16' Group I had a carrier rate of 12.2% and Group II, 14.1%. Virtually all group A strains were typable and those isolated from patients belonged to five prevalent types.arly studied and followed for streptococcal infection
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The incidence of cirrhosis and primary hepatic carcinoma in the autopsy material is studied. in 4389 autopsies performed, during the last 9 years we found 134 (3%) cases of cirrhosis and 24 (0.5%) cases of primary hepatic carcinoma. The majority of the patients were from NorthWest and west part of the city. of the 134 cases of cirrhosis 90 correspond to the portal type, 24 to the post-necrotic type, 12 to the biliary cirrhosis, 6 to the post-hepatitis cirrhosis and two cardiac cisrhosis. 19 of our 134 cases of cirrhosis, occured in children between the age of 4months to 13 years. The liver of the 90 cases diagnosed, Portal cirrhosis were characterized grossely by weights from 510-2800 Gr and fine uniformly nodular surface. Micscopically there was marked, fatty change of hepatic cells, focal and spotty necrosis and delicated fibrillary tongue, interconnecting portal spaces. of the 24 cases post-necrotic cirrhosis 4 had had (26%) an antecedent jaundice. The liver ranged, from 700-2500 gr., presenting broad scarring and coars nodules. In bur six cases, Post-hepatitic cirrhosis, the liver were redish brown, and presented uniform nodules, 0,5 to 1.5 Cm. in diameter. Liver weights varried form 850 to 1200 Gr. Microscopically 17 cases of carcinoma were hepato-carcinoma, two presented mixed structures of hepatoma and 5 cases were cholangio Carcinoma. Six of hepatomas showed previous portal cirrhosis and one mixed carcinoma showed previous portal cirrhosis.
